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| Efficacy of oxygen therapy on blood pressure and heart rates of contruction workers in plateau of different altitudes |
| CHEN Jianhua1,ZHENG Bihai2,YAN Yiping1,LI Shenghui1,ZHENG jianbao2,GUO Jun1,WAN Ronghui1 |
| 1. Second Corps Hospital of Armed Police Hydropower, Nanchang 330001， China； 2. The Mountain Sickness Institute, Tibet Military General Hospital, Lhasa 850000, China |
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Abstract Objective Oxygen, To observe the changes in blood pressure and heart rates before and after oxygen therapy in onstruction workers and their correlation with different altitudes. Methods Different altitude construction workers, in heights of elevation 3000 m, 3500 m, 4000 m, 4500 m and 5000 m, 200 ground and high-altitude construction workers each, inhaled 93% concentration oxygen mask flow of 5 L / min every 1 h, to monitor the heart rate and blood pressure changes on 3,7,15,30,60 d in the plateau. Before and after the oxygen therapy, their blood pressure, heart rate variability and its correlation were observed. Results After oxygen therapy, the heart rates and the blood pressure were significantly reduced with increasing altitude, most obviously 7-15 days after access to the plateau. The rate of changes in blood pressure changes after oxygen therapy in accordance with plateau hypertension was only 5.4%, with significant differences (P<0.01). Partial correlation analysis showed that in the oxygen group, heart rate and systolic blood pressure, diastolic blood pressure and heart rate pressure product were positively correlated in the altitude of 4000 m or higher. In the group without oxygen therapy, the heart rate, oxygen consumption, the hypoxic pressor response, and blood pressure were higher. Conclusion High-altitude construction workers in the plateau receiving early oxygen therapy can reduce the impact of the plateau low atmospheric pressure and hypoxia on their heart rates and blood pressure.
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Received: 11 June 2012
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张雪峰，孙利民，崔国华．人到高原-卫生知识与疾病防治［M］．西宁：青海人民出版社，2001：49-50.［2］ 张 岚，张庆军，李 阳，等.湖北省35岁以上高血压病流行状况调查［J］.公共卫生与预防医学,2007，18（1）：29-35.［3］ 付东红，王 玮，和世平.高血压患者血压与心率乘积检测及临床意义［J］.华西医学,2000,15（2）：204-205.［4］ 陈建华，郑必海，严亦平，等.由平原进入高海拔地区施工人员血压动态变化情况研究［J］.临床和实验医学杂志,2011,22（10）:1740-1743.［5］ 许晓巍，俞康龙，沈 芸，等.氧疗方式和氧流量与鼻前庭氧分压变化的关系［J］.临床急诊杂志,2009,10（1）:17-19.［6］ 孔 亮，车 杰，张建鹏，等.在3992m海拔高度吸氧及局部增压对高原缺氧疗效的对比研究［J］.中国呼吸与危重监护杂志,2009，7（8）4：392-395.［7］ West J B.Potential use of oxygen enrichment of room air in mountain resorts［J］.High Alt Med Biol,2001,3(1)：59-64.［8］ West J B.Commuting to high altitude:value of oxygen enrichment of room air［J］.High Alt Med Biol,2001,3(2)：223-235.
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张雪峰，孙利民，崔国华．人到高原-卫生知识与疾病防治［M］．西宁：青海人民出版社，2001：49-50.［2］ 张 岚，张庆军，李 阳，等.湖北省35岁以上高血压病流行状况调查［J］.公共卫生与预防医学,2007，18（1）：29-35.［3］ 付东红，王 玮，和世平.高血压患者血压与心率乘积检测及临床意义［J］.华西医学,2000,15（2）：204-205.［4］ 陈建华，郑必海，严亦平，等.由平原进入高海拔地区施工人员血压动态变化情况研究［J］.临床和实验医学杂志,2011,22（10）:1740-1743.［5］ 许晓巍，俞康龙，沈 芸，等.氧疗方式和氧流量与鼻前庭氧分压变化的关系［J］.临床急诊杂志,2009,10（1）:17-19.［6］ 孔 亮，车 杰，张建鹏，等.在3992m海拔高度吸氧及局部增压对高原缺氧疗效的对比研究［J］.中国呼吸与危重监护杂志,2009，7（8）4：392-395.［7］ West J B.Potential use of oxygen enrichment of room air in mountain resorts［J］.High Alt Med Biol,2001,3(1)：59-64.［8］ West J B.Commuting to high altitude:value of oxygen enrichment of room air［J］.High Alt Med Biol,2001,3(2)：223-235.
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2013, Vol. 24 
