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| Effect of epidural ketamine on shivering in transurethral resection of prostate |
| CHENG Gansheng,SHAO Qingzhu,MAO Tian,PAN Mian |
| Department of Anesthesiology, Nanjing Branch Hospital of Jiangsu Provincial Corps Hospital of Chinese People’s Armed Police Forces, Nanjing 210028， China |
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Abstract Objective To investigate the effect of epidural ketamine on shivering in transurethral resection of the prostate (TURP). Methods Ninety-three male patients scheduled for TURP under epidural anesthesia were enrolled in this study. Patients were randomly divided into three groups. Group 1 consisted of 31 patients who received epidural 0.75% ropivacaine, group 2 consisted of 32 patients who received epidural ketamine (0.2 mg/kg) in addition to 0.75% ropivacaine, and group 3 consisted of 30 patients who received epidural ketamine (0.4 mg/kg) in addition to 0.75% ropivacaine. Shivering and side effects such as hypotension, bradycardia, nausea, and hallucination were recorded during the anesthesia and for 2 hours while in the postanesthetic recovery room. Results Shivering was statistically more frequent in group 1 than in the other groups and the incidences of side effects such as hypotension, bradycardia, and nausea were significantly higher in group 1 than in the other groups (P<0.05). The incidence of sedation was significantly higher in group 3 than in the other groups (P<0.05). Conclusions In patients who undergo TURP under epidural anesthesia, the prophylactic use of low-dose epidural ketamine would be helpful in preventing any adverse effects, including shivering.
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Received: 13 September 2012
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2013, Vol. 24 
