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| Blood glucose, glycosylated hemoglobin and glycosylated serum protein three combined detection in the clinical research |
| CHEN Mengchun. |
| Department of Laboratory Medicine, Zhejiang Provincial Corps Hospital, Chinese People’s Armed Police Forces,Jiaxing 314000,China |
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Abstract Objective To investigate the clinical application value of blood glucose (Glu), glycosylated hemoglobin (HbA1c), and glycosylated serum protein (GSP) three combined detection. Methods Eighty patients clinically diagnosed as having type 2 diabetes mellitus underwent Glu, HbA1c and GSP determinations before and after treatment, and another 80 healthy subjects were recruited as the control group. The results were analyzed statistically. Results In diabetic patients the fasting Glu, HbA1c and GSP levels were significantly higher than those in normal control group. And in diabetic group the fasting blood glucose and HbA1c and GSP were positively correlated; the results of the three determinations were statistically significantly different (P<0.05). Conclusions Glu, HbA1c and GSP three combined detection is important in early diagnosis of type II diabetes mellitus; it helps assess therapeutic results, control and reduce the incidence and development of diabetic complications.
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Received: 25 October 2012
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叶红英, 俞茂华, 陈灏珠.实用内科学［M］.北京: 人民卫生出版社, 2005: 1041.［2］ 赵 岩, 林风武, 殷国光.空腹血糖及糖化血红蛋白用于筛查糖耐量减退的比较性研究［J］.中国实验诊断学, 2006, 10(4): 389-391.［3］ Krishnamnrti U, Stelfes M W.Glycohemoglobin: a primary predictor of the development or reversal of complications of diabetesmellitus［J］.Clin Chem, 2007, 47: l157-1165.［4］ 许 翔, 丁莉莉.血清糖化白蛋白检测在糖尿病控制中的应用［J］.实用医技杂志, 2006, 2(3): 340-341.［5］ 马文新. HbA1c的临床意义及常规检测方法［J］.世界医疗器械杂志, 2001, 7(8): 14-17.［6］ 曹登成.糖化血红蛋白、果糖胺在临床检测中的重要性［J］.中华医药杂志, 2005, 5（10）: 44.
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叶红英, 俞茂华, 陈灏珠.实用内科学［M］.北京: 人民卫生出版社, 2005: 1041.［2］ 赵 岩, 林风武, 殷国光.空腹血糖及糖化血红蛋白用于筛查糖耐量减退的比较性研究［J］.中国实验诊断学, 2006, 10(4): 389-391.［3］ Krishnamnrti U, Stelfes M W.Glycohemoglobin: a primary predictor of the development or reversal of complications of diabetesmellitus［J］.Clin Chem, 2007, 47: l157-1165.［4］ 许 翔, 丁莉莉.血清糖化白蛋白检测在糖尿病控制中的应用［J］.实用医技杂志, 2006, 2(3): 340-341.［5］ 马文新. HbA1c的临床意义及常规检测方法［J］.世界医疗器械杂志, 2001, 7(8): 14-17.［6］ 曹登成.糖化血红蛋白、果糖胺在临床检测中的重要性［J］.中华医药杂志, 2005, 5（10）: 44.
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2013, Vol. 24 
