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| Effects of smoking and smoking cessation on arterial hardness in healthy subjects |
| SUN Jingjie and ZHAO Chunhua. The Sanatorium of Chinese People’s Armed Police Forces,Sanya 572000,China |
| The Sanatorium of Chinese People’s Armed Police Forces, Sanya 572000, China |
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Abstract Objective To study the effects of smoking and smoking cessation on arterial hardness in healthy subjects. Methods Seventy-five chronic smoking healthy subjects were divided into maintaining smoking group (n=26) and ex-smoking group (n=21).Another 28 no-smoking healthy subjects were used as control group. The arterial hardness reflected by baPWV(brachial-ankle pulse wave velocity) was compared at baseline and after 1 month or 6 months of smoking cessation. Results The maintaining smoking group and ex-smoking group had higher values of baPWV than no-smoking group at baseline(P<0.05). After 1 month of smoking cessation, there was no difference in baPWV between maintaining smoking group and ex-smoking group(P>0.05), the same as between pre- and post-smoking cessation(P>0.05). After 6 month of smoking cessation, there was a decline in baPWV in ex-smoking group, when compared with maintaining smoking group(P<0.05). The same decrease was also observed between pre- and post-smoking cessation(P<0.05). Conclusions Smoking is associated with a decline of the arterial compliance, and 1 month of smoking cessation does not improve the arterial elasticity. But 6 months of smoking cessation improves the arterial elasticity.
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Received: 23 December 2012
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Kubozono T, Miyata M, Ueyama K, et al. Acute and chronic effects of smoking on arterial stiffness[J]. Circulation journal : official journal of the Japanese Circulation Society, 2011,75(3):698-702.
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O’Rourke M F, Hashimoto J. Mechanical factors in arterial aging: a clinical perspective[J]. Journal of the American College of Cardiology, 2007,50(1):1-13.
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2013, Vol. 24 
