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| Correlation between lipoprotein (a) serum levels and coronary heart disease and cerebral infarction |
| LI Zhenzhou1,YANG Changchun2,HUANG Jiajia1,LI Kai2,and ZHOU Rui1. |
1. Department of Cadre Ward No
2. Department of South Biulding, General Hospital of Chinese People’s Armed Police Forces. Beijing 100039, China |
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Abstract Objective To investigate the changes of serum lipoprotein(a)(Lpa) in patients with coronary heart disease and cerebral infarction, and to provide a basis for the prevention and treatment of cardiovascular and cerebrovascular diseases. Methods The Lp(a) was detected by latex agglutination turbidimetry in coronary heart disease patients and cerebral infarction patients,and the hypertension and diabetes patients of their high-risk groups were also observed. Healthy persons served as control group. Results (1)Compared with control group, Lp(a) abnormal proportions were significantly higher in coronary heart disease and cerebral infarction patients groups, also in the hypertension and diabetes patient groups(P<0.05).In the patient groups, Lp(a) serum levels were also obviously elevated, but only in coronary heart disease,cerebral infarction and diabetes patients were statistically significantly higher (P<0.05). (2)For age group, only in coronary heart disease group, Lp(a) serum level was significantly higher in patients ≥60 age than that in patients <60 age (P<0.05). Conclusions Lipoprotein(a) levels are closely related to the occurrence of coronary heart disease and cerebral infarction. The lipoprotein(a) may be an independent risk factor for cardiovascular and cerebrovascular diseases development.
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Received: 20 February 2013
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2013, Vol. 24 
