99mTc-MIBI双时相显像对继发性甲状旁腺功能亢进症的诊断价值

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Abstract Objective To evaluate the clinical value of ^99mTc-MIBI double-phase imaging in the secondary hyperparathyroidism. Methods On 58 patients with diagnostic or suspicious secondary hyperparathyroidism, the ^99mTc-MIBI double-phase imaging was performed at early (20 min) and late (2 hours) phase, and all of them underwent neck ultrasonography. Final diagnosis was obtained by pathological result, serum IPTH test, and clinical follow-up. 52 cases were confirmed as having hyperparathyroidism and 6 were excepted. Among them 25 cases obtained pathological results (10 with hyperplasia, 9 with hyperplasia and adenoma, and 6 with adenoma). Results 49 true positive cases, 1 false positive case, 5 true negative cases and 3 false negative cases were validated. The sensitivity, specificity and accuracy of ^99mTc-MIBI double-phase imaging in the diagnosis of secondary hyperparathyroidism were 94.2%, 83.3%, 93.1%, respectively. 114 foci of hyperparathyroidism were detected by ^99mTc-MIBI double-phase imaging, of them 14 cases with 1focus, 21 with 2 foci, 14 with 3 foci or more. The sensitivity, specificity and accuracy of neck ultrasonography in the diagnosis of secondary hyperparathyroidism were 88.5%, 50%, 84.4%, respectively. Conclusion ^99mTc-MIBI double-phase imaging is useful in the diagnosis and localization of secondary hyperparathyroidism and should be taken as routine before operation.

Key words： hyperparathyroidism radionuclide imaging ^99mTc-MIBI

Received: 17 January 2013

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	Articles by authors
	LI Fei
	ZHANG Chi
	ZHANG Haiying
	CAI Li
	ZHOU Weihua
	PU Chaoyu
	CHEN Yan
	and MAO Xinyuan.

Cite this article:

LI Fei,ZHANG Chi,ZHANG Haiying等. Value of ^99mTc-MIBI double-phase imaging in diagnosis of secondary hyperparathyroidism[J]. Med. J. Chin. Peop. Armed Poli. Forc., 2013, 24(6): 471-473.

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http://journal08.magtechjournal.com/Jwk_wjyx/EN/ OR http://journal08.magtechjournal.com/Jwk_wjyx/EN/Y2013/V24/I6/471

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