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| High-flux hemodialysis combined with L-carnitine in treatment of 56 uremic patients with refractory anemia |
| REN Yongqiang1,XUE Mei1,and CUI Zhiru2. |
1. Department of Nephrology, The Third Hospital of Beijing Municipal Corps,Chinese People’s Armed Police Forces,Beijing 100141,China;
2. Department of Nursing, Inner Mongolia Autonomous Region Corps Hospital, Chinese People’s Armed Police Forces, Hohehot 010040, China |
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Abstract Objective To study the effect of high-flux hemodialysis combined with levocarnitine on uremic pationts with refractory anemia. Methods Fifty-six patients with refractory anemia in maintenance hemodialysis were randomly divided into 4 groups: normal group ( 14 cases) underwent conventional hemodialysis, 3 times a week; L-carnitine group (14 cases) was given levocarnitine 1 g on common hemodialysis basis, 3 times a week; high-flux dialysis group (14 cases) received high- flux hemodialysis,3 times a week; high-flux hemodialysis plus L-carnitine group (14 cases) was given levocarnitine 1 g on high-flux hemodialysis basis, 3 times a week. Blood routine and biochemical indicators were examined after treatment for 3 and 6 months, and statistical analysis was made. Results The conventional hemo dialysis group and L-carnitine group had no improvement in anemia; high-flux hemo dialysis group and high-flux hemodialysis plus L-carnitine group improved in anemia, with statistically significant difference, compared with the conventional hemodialysis group (P＜0.05); high-flux hemodialysis combined with L-carnitine group, compared with high-flux hemodialysis group, had remarkable curative effect, with statistically significant difference ( P＜0.05 ). Conclusion High-flux hemodialysis combined with L-carnitine is effective in the treatment of uremic patients with refractory anemia
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Received: 01 March 2013
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2013, Vol. 24 
