偏头痛患者磁共振弥散张量成像的初步探讨

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Abstract Objective To study the white matter lesions in migraineurs by diffusion tensor imaging (DTI). Methods Seventeen migraineurs and sixteen healthy controls were recruited and examined with DTI in the General Hospital of PLA between February 2006 and April 2008. Apparent diffusion coefficient (ADC) and fractional anisotropy (FA) in the normal appearing while matter(NAWM) of region of interests (ROIs) in frontal lobe, periventricular and occipital lobes were measured in each group. The data were analyzed by independent t-test. Results The ADC of periventricular NAWM in migraineurs was significantly higher than that in healthy controls(P<0.05). The FA of occipital lobe NAWM in migraineurs was significantly lower than that in healthy controls(P<0.01). Conclusion DTI is valuable to determine the early lesions of white matter in migraineurs .

Key words： migraine white matter lesions diffusion tensor imaging

Received: 23 January 2013

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http://journal08.magtechjournal.com/Jwk_wjyx/EN/ OR http://journal08.magtechjournal.com/Jwk_wjyx/EN/Y2013/V24/I7/588

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