|
|
|
| Effects of high dose radiotherapy combined with osteoclast inhibitors on pain caused by osseous metastasis |
| WU Lizhou1,JIANG Mingdong2,YANG Wanyi2,FANG Liang2,and WANG Zhenghong2 |
| WU Lizhou1, JIANG Mingdong2, YANG Wanyi2, FANG Liang2, and WANG Zhenghong2. 1.Tumor Radiotherapy Center, Jiangsu Provincial Corps Hospital of Chinese People’s Armed Police Forces, Yangzhou 225003, China; 2. Tumor Hematology and Radiation Therapy Center, Chongqing Ninth People’s Hospital, Chongqing 400700, China |
|
|
|
|
Abstract Objective To investigate the clinical effects of high dose radiotherapy combined with osteoclast inhibitors on pain caused by osseous metastasis. Methods 550 malignant tumor patients were divided into treatment group(n=300) and control group(n=250).Treatment group was given high dose radiotherapy combined with osteoclast inhibitors.The control group was only received osteoclast inhibitors or else drugs. Results The efficiency of partial response plus complete response was significantly higher in treatmen group than those in control group (75.6% vs 39.60%, P<0.05). And the long-term response rate was also better than that in control group (85.6% vs 48.8%, P<0.05). Conclusions High dose radiotherapy combined with osteoclast inhibitors has good short and long-term clinical efficacy for pain caused by osseous metastasis.
|
|
Received: 03 April 2014
|
|
|
|
|
|
| [2] |
王玉名, 商冠宁, 孙 平.唑来膦酸治疗骨转移癌疼痛的临床研究[J].中国民康医学, 2010, 22(2):97-98.
|
| [1] |
黄聪超.止痛散治疗骨转移癌疼痛的临床观察[J].山西中医学院学报, 2010, 11(4):58-59.
|
| [3] |
王 岩, 王华庆. 鲑鱼降钙素联合放疗治疗恶性肿瘤骨转移疗效分析[J].武警医学院学报, 2011, 20(9):704-706.
|
| [2] |
王玉名, 商冠宁, 孙 平.唑来膦酸治疗骨转移癌疼痛的临床研究[J].中国民康医学, 2010, 22(2):97-98.
|
| [4] |
王 勤 , 佘明金.不同分割方式放射治疗恶性肿瘤骨转移的临床疗效观察[J].武警医学院学报, 2009, 18(11):965-966.
|
| [5] |
黄河澄, 林连光, 罗何三, 等.放疗联合唑来磷酸治疗骨转移瘤疗效比较分析[J].吉林医学, 2012, 33(4):687-688.
|
| [3] |
王 岩, 王华庆. 鲑鱼降钙素联合放疗治疗恶性肿瘤骨转移疗效分析[J].武警医学院学报, 2011, 20(9):704-706.
|
| [4] |
王 勤 , 佘明金.不同分割方式放射治疗恶性肿瘤骨转移的临床疗效观察[J].武警医学院学报, 2009, 18(11):965-966.
|
| [6] |
李文竹, 王长胜, 张玉书.骨转移癌不同剂量分割放疗止痛疗效分析[J].实用医学杂志, 2006, 22(4):420-421.
|
| [5] |
黄河澄, 林连光, 罗何三, 等.放疗联合唑来磷酸治疗骨转移瘤疗效比较分析[J].吉林医学, 2012, 33(4):687-688.
|
| [7] |
Donato V, Bonfili P, Bulzonetti N, et al. Radiation therapy for oncological emergencies[J]. Anticancer Res, 2001, 21(3c):2219.
|
| [8] |
陈志霄, 周道安. 肺癌骨转移的放疗效果及相关预后因素分析[C]. 第五届全国肿瘤放疗及综合治疗会议论文集, 2007, 4:312-313.
|
| [6] |
李文竹, 王长胜, 张玉书.骨转移癌不同剂量分割放疗止痛疗效分析[J].实用医学杂志, 2006, 22(4):420-421.
|
| [7] |
Donato V, Bonfili P, Bulzonetti N, et al. Radiation therapy for oncological emergencies[J]. Anticancer Res, 2001, 21(3c):2219.
|
| [8] |
陈志霄, 周道安. 肺癌骨转移的放疗效果及相关预后因素分析[C]. 第五届全国肿瘤放疗及综合治疗会议论文集, 2007, 4:312-313.
|
|
|
|
2014, Vol. 25 
