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| Analysis of multi-resistant bacteria detected in this hospital from January 2010 to december 2012 |
| HE Huili1,LI Dongmei1,LIU Hua1,CAO Junping2,ZHANG Jie1,LIU Yang1 |
1.Department of Pharmacy, General Hospital of Chinese People’s Armed Police Forces, Beijing 100039, China;
2. Department of Supply, General Hospital of Chinese People’s Armed Police Forces, Beijing 100039, China |
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Abstract Objective To investigate the application of optimal antimicrobial therapies to controlling the increase of multidrug-resistant organisms. Methods Hospital rational use of antimicrobial drugs by strengthening the basic application and characteristics of generally used antimicrobial agents, early use of sensitive drugs based on the patient’s condition and constitution were encouraged. From January 2010 to December 2012, multidrug-resistant organisms were analyzed from various types of specimens. Results From January 2010 to December 2012, the annual proportion of bacterial strains slightly turned down (71.1% vs.59.3%), multidrug resistent organisms (MDRO). MDRO decreased slightly (2.70% vs.2.35%), with no significant difference (P>0.05). Detection of MDRO was significantly reduced from 0.19% to 0.14% (P<0.05). From January 2010 to December 2012, the detection rate of Klebsiella pneumoniae, Acinetobacter baumannii, MRSA and Pseudomonas aeruginosa all reduced from 0.4‰ to 0.3‰, methicillin resistant Staphylococcus aureus(MRSA) from 0.4‰ to 0.3‰. The proportions of Acinetobacter baumannii and MRSA were reduced from 23.0% to 19.1%, and 23.7% to 20.4%, respectively. Conclusions Reasonable selection of antibiotics can control the increase of multidrug-resistant organisms.
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Received: 09 June 2013
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2014, Vol. 25 
