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| Comparison of three radiotherapy techniques for bilateral Grave’s ophthalmopathy |
| ZHAO Weidong1,NING Jian1,ZHAO Shuixi2,SUN Huadong1,MU Xiaofeng1 |
1. Center of Radiotherapy, General Hospital of Chinese People’s Armed Police Forces,Beijing 100039,China;
2. First Department of Oncology,General Hospital of Chinese People’s Armed Police Forces,Beijing 100039,China |
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Abstract Objective To study the implementation and dosimetric advantages of three-dimensional conformal irradiation (3DCRT) including electron beam irradiation field in the treatment of bilateral Grave’s ophthalmopathy. Methods All the ten patients diagnosed as having bilateral Grave’s ophthalmopathy were scheduled for such three techniques including three-dimensional conformal irradiation, the conventional opposing field irradiation (OF) and the mainstream intensity modulated irradiation (IMRT) in recent years. Dose distribution diagrams, dose volume histograms and dosimetric parameters of the planning target volume (PTV) and organs at risk (OARs) were compared. Results For D98%,V95%,Dmean, CI and HI in PTV parameters, Dmin, Dmean and Dmax in bilateral lens parameters, Dmin,Dmean in bilateral lacrimal glands parameters , 3DCRT and IMRT compared with OF were statistically significantly different (P<0.05), while no significant difference was found between 3DCRT and IMRT technique,for D2% in PTV parameters and Dmax in bilateral lacrimal glands parameters, the comparison between such three technologies were not statistically significantly different (P>0.05). Conclusions 3DCRT (including electron beam irradiation field) and IMRT technology have as many dosimetric advantages as OF technology. This technology can replace IMRT technology if patients are unwilling to accept IMRT due to its price or no IMRT equipment can be acquired.
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Received: 25 February 2014
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2014, Vol. 25 
