3种胃肠重建方式对2型糖尿病降糖效果的meta分析

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Abstract Objective To compare the hypoglycemic effects of Billroth Ⅰ, Billroth Ⅱ, Roux-en-y gastrointestinal reconstruction operations on type 2 diabetes mellitus. Methods The literature(1994.01-2013.10)was searched about different digestive tract reconstruction operations published on the comparison of curative effect of type 2 diabetes mellitus in CBM, CMCC,CNKI, VIP, WANFANG, MEDLINE, then screened, extracted, quality was evaluated. Meta-analysis was performed by using RevMan5.0 software. Results A total of 7 articles were selected.The total numbers of cases in 378 cases,were 74 in Billroth Ⅰ, 184 in Billroth Ⅱ, and 120 in Roux-en-y. The Results of meta-analysis were as follows: (1) The blood glucose levels in Billroth Ⅰ, Billroth Ⅱ and Roux-en-y in the third month after operation were significantly lower than those preoperation. (2) No difference in blood glucose levels between Billroth Ⅰ and Billroth Ⅱ in the third month after operation. (3) The blood glucose levels in Billroth Ⅰ were significantly higher than those of Roux-en-y in the third month after operation. (4) No difference in blood glucose levels between Billroth Ⅱ and Roux-en-y in the third month after operation. (5) Half a year after operation ,the blood glucose level of Billroth I was significantly higher than that of Billroth Ⅱ and Roux-en-y.(6) Compared with Billroth Ⅱ and Roux-en-y, no difference in blood glucose levels after half a year of the operation.(7) Comparism of preoperation and six months after Billroth I operation, showed no difference in blood glucose.(8) The blood glucose levels of Billroth Ⅱ and Roux-en-y after half a year of the operation were significantly lower than that of the preoperation.(9) For Billroth Ⅱ compared with Roux-en-y, there were no differences in diabetes treatment results. Conclusions The Billroth Ⅱ and Roux-en-y operations for the treatment of type 2 diabetes mellitus are effective.

Key words： Billroth Ⅰ Billroth Ⅱ Roux-en-y type 2 diabetes mellitus blood glucose meta-analysis

Received: 12 March 2014

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	LI Fei
	HAN Cheng-Xin
	JIA Yuan-Li
	ZHENG Hao
	DA Bu

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LI Fei,HAN Cheng-Xin,JIA Yuan-Li等. Hypoglycemic effects of three types of gastrointestinal reconstruction on type 2 diabetes mellitus:a meta-analysis[J]. , 2014, 25(8): 803-807.

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http://journal08.magtechjournal.com/Jwk_wjyx/EN/ OR http://journal08.magtechjournal.com/Jwk_wjyx/EN/Y2014/V25/I8/803

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