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| Comparison of four commercially available assays for antibody to hepatitis B virus surface antigen |
| ZHANG Xiaoli1,WANG Ruiling1,SONG Na1, WANG Wenjing1, ZHANG Cui1,ZHANG Xuedong2, WANG Chongchong2,and YANG Xiaoli1 |
1.Clinical laboratory, General Hospital of Chinese People’s Armed Police Forces,Beijing 100039,China.
2. Autobio Diagnostics Co Ltd, Zhengzhou 450016, China |
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Abstract Objective To study four commercially available assays for antibody to hepatitis B virus surface antigen. Methods A total of 252 specimens were tested by Abbott i2000、Roche e601、Autobio AutoLumoA2000 and a ELISA kit, respectively,and the quantitative results and the performance characteristics of the different test systems were compared. Results The sensitivity and specificity of different manufacturer kits for Anti-HBs were beyond 93%. The detection rates of compared CLIA(Chemiluminescence Immunoassay) commercial Anti-HBs reagents had no significant difference (P>0.05). Conclusions The four commercial Anti-HBs reagents have false positive and false negative results; the correlation analysis for quantitative results is beyond 0.85.
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Received: 13 June 2014
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2014, Vol. 25 
