仪仗兵训练性血红蛋白尿发病机制及其影响因素探讨

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Abstract Objective To study the possibility of honor guard training-induced hemoglobinuria, occurring mechanism and influencing factors. Methods To observe the soldiers’ blood erythrocyte malondialdehyde (MDA), superoxide dismutase (SOD), and plasma total antioxidant capacity (T-AOC), blood lactate (BLA) changes before and after a routine training in the honor guard, and divide them into two groups with whether they developed naked eye “hematuria” repeatly in order to observe the change in the index of and correlation with “the naked eye hematuria”. Results The MDA before training(6.57±0.64)nmol/mg, after training (6.86±0.67) nmol/mg; SOD before training (9.61±1.08) U/mg, after training (10.46±2.12 )U/mg; T-AOC before training 5.18 (3.70-6.11) U/ml, after training (7.09-9.81) U/ml; BLA before training (21.4±5.4) mmol/L, after training (31.8±12.8) mmol/L. MDA, SOD, T-AOC, BLA after training increased compared with those before training increased, with statistical significance (P<0.05). Difference in MDA, SOD, T-AOC (P<0.05) existed with correlation hematuria before and after training. Conclusions The honor guards’ antioxidant capacity of red blood cell, is changed by usual training; it may be one of the causes of training-induced hemoglobinuria.

Key words： oxidative stress osmotic pressure mechanical damage deformability of red cell;hematuria

Received: 02 July 2014

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	HE Zongze
	LI Jijun
	CHEN Fengkun

Cite this article:

HE Zongze,LI Jijun,CHEN Fengkun. Clinical study on mechanism of training-induced hemoglobinuria in honor guard[J]. Med. J. Chin. Peop. Armed Poli. Forc., 2014, 25(10): 1032-1034.

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http://journal08.magtechjournal.com/Jwk_wjyx/EN/ OR http://journal08.magtechjournal.com/Jwk_wjyx/EN/Y2014/V25/I10/1032

[4]	朱梅菊,屈菊兰,李红.螺旋藻及其复方对运动小鼠红细胞形态及自由基代谢的影响[J].中国运动医学杂志,2003,22(5):506-508.
[5]	Simpson R J,Wilson M R,Black J R,et al.Immune alteration,lipid peroxidation,and muscle damage follow-ing ahill race[J].Can J Appl Physiol,2005,30(2):196-211.
[1]	李冀军,陈凤锟,张国恩,等.仪仗兵训练性血红蛋白尿的临床初步观察[J].感染、炎症、修复,2004,5(1):46-48.
[2]	张冉,石青.长跑训练后血尿21例原因分析[J].总装备部医学学报,2012,14(4):221-222.
[6]	潘兴时.螺旋藻对运动大鼠红细胞超氧化歧化酶和丙二醛的影响[J].中国实用医药,2010,5(13):81-82.
[7]	Powers S K,Lennon S L. Analysis of cellular responses to free radicals:focus on exercise and skeletal muscle[J].Pro Nutr Soc,1999,58(4):1025-1033.
[3]	李翠珍,贾静.力竭游泳对大鼠红细胞膜脂质过氧化及红细胞变形性的影响[J].中国临床康复,2005,9(28):198-199.
[8]	Fulles P,Mecocci P,Fano G, et al. Specific cxidative alteration in vastus lateralis muscle of patients with the diagnosis of chronic fatigue syndrome[J].Free Radic Biol Med,2000,29(12):1252-1259.
[9]	张慧,苏全生.联合抗氧化剂对一次大强度运动后运动员T-AOC、SOD、GSH-px及MDA的影响[J].中国体育大学学报,2008,31(4):483-485.
[4]	朱梅菊,屈菊兰,李红.螺旋藻及其复方对运动小鼠红细胞形态及自由基代谢的影响[J].中国运动医学杂志,2003,22(5):506-508.
[5]	Simpson R J,Wilson M R,Black J R,et al.Immune alteration,lipid peroxidation,and muscle damage follow-ing ahill race[J].Can J Appl Physiol,2005,30(2):196-211.
[6]	潘兴时.螺旋藻对运动大鼠红细胞超氧化歧化酶和丙二醛的影响[J].中国实用医药,2010,5(13):81-82.
[7]	Powers S K,Lennon S L. Analysis of cellular responses to free radicals:focus on exercise and skeletal muscle[J].Pro Nutr Soc,1999,58(4):1025-1033.
[8]	Fulles P,Mecocci P,Fano G, et al. Specific cxidative alteration in vastus lateralis muscle of patients with the diagnosis of chronic fatigue syndrome[J].Free Radic Biol Med,2000,29(12):1252-1259.
[9]	张慧,苏全生.联合抗氧化剂对一次大强度运动后运动员T-AOC、SOD、GSH-px及MDA的影响[J].中国体育大学学报,2008,31(4):483-485.

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