HR-HPV检测在宫颈细胞学异常患者中的意义

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Abstract Objective To investigate the application value of HR-HPV testing in cervical lesion screening. Method 872 patients interpreted as having abnormal cervical cytology received HR-HPV testing and all patients underwent colposcopy and biopsy. The patients were divided into five groups of NILM, CINI, CINII, CINIII and ICC. Association between HR-HPV load and CINs were evaluated by Spearman rank correlation. Result The positive rates of HR-HPV in ASC-US, ASC-H, LSIL, HSIL were 31.6%, 59.7%, 50.3%, 89.6%, respectively(P<0.01). The positive rates of HR-HPV in NILM, CINI, CINII, CINIII and ICC were 25.2%, 53.4%, 86.7%, 96.4%, 100%, respectively(P<0.01). There was significant difference between the viral load in NILM and CINs or ICC,while no significant difference was observed among the viral load in CINI, CINII, CINIII and ICC. Conclusions The positive rate of HR-HPV increases with the gravity of cervical lesion. The HR-HPV viral load is significantly associated with the presence of CINs and ICC. HPV viral load does not increase with severity of cervical neoplasia.

Key words： human papillomavirus cytology viral load

Received: 20 February 2014

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	Articles by authors
	ZHANG Xiaoyan
	DING Xiaoping
	YE Mei
	BIAN Meilu
	CHEN Qingyun

Cite this article:

ZHANG Xiaoyan,DING Xiaoping,YE Mei等. Application of high-risk human papillomavirus testing in women with cervical abnormal cytology[J]. Med. J. Chin. Peop. Armed Poli. Forc., 2014, 25(10): 983-986.

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http://journal08.magtechjournal.com/Jwk_wjyx/EN/ OR http://journal08.magtechjournal.com/Jwk_wjyx/EN/Y2014/V25/I10/983

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