胸部钝挫伤患者心肌标志物水平的变化及其诊断意义

Abstract
Figure/Table
References
Related Citation (9)

Download: PDF (0 KB) HTML (1 KB)
Export: BibTeX | EndNote (RIS)

Abstract Objective To investigate the dynamic changes of myocardial injury markers in blunt trauma patients’ serum and its significance in diagnosis of trauma complicated by myocardial injury. Methods According to the presence or absence of myocardial injury, 82 cases of blunt trauma patients (ISS≥16) from December 2011 to December 2013 in this hospital were assigned to group A (presence of myocardial injury) and B (absence of myocardial injury). Troponin Ⅰ (cTnI), heart fatty acid-binding protein (H-FABP) , and myoglobin (Mb) were detected 3 h, 6 h, 12 h, 48 h after injury in serum of group A, B and 60 healthy persons (control group). Results Concentrations of cTnI, H-FABP and Mb were significantly higher than those in the control group at different times. Concentrations of cTnI and H-FABP in group A were significantly higher than those in group B (P<0.01). The concentration of Mb in group A, B was higher than that in control group, but the difference between the groups A and B was not significant (P＞0.05). Conclusions There is a good correlation between the dynamic changes of cTnI, H-FABP and Mb in serum and severity of illness, variation tendency and prognosis of blunt chest trauma patients, which is important for early diagnosis and treatment of myocardial injury. Combined with other examination Methods (X-ray, ECG, blood gas analysis, color Doppler echocardiography), detection of myocardial injury markers has a high clinical value in treatment of blunt chest trauma complicated by myocardial injury.

Key words： thoracic blunt injury myocardial damage troponin I heart-type fatty acid-binding protein myoglobin

Received: 10 June 2014

ZTFLH:	R655
	R542.2

	Service

	E-mail this article
	Add to my bookshelf
	Add to citation manager
	E-mail Alert
	RSS
	Articles by authors
	JIANG Lvquan
	ZHENG Jian
	CHEN Jian
	WU Hao
	CHEN Linsong

Cite this article:

JIANG Lvquan,ZHENG Jian,CHEN Jian等. Dynamic changes and clinical singnificance of myocardium marker in thoracic blunt injury[J]. Med. J. Chin. Peop. Armed Poli. Forc., 2015, 26(1): 8-10.

URL:

http://journal08.magtechjournal.com/Jwk_wjyx/EN/ OR http://journal08.magtechjournal.com/Jwk_wjyx/EN/Y2015/V26/I1/8

[1]	黄标通, 龙建平.心脏钝性损伤的诊疗进展[J]. 实用医学杂志, 2009, 25(19) :3179-3180.
[2]	盛大平, 徐元宏, 沈继录, 等.心肌损伤标志物的临床应用价值[J].国际检验医学杂志, 2011, 32(8):896-897.
[3]	马依彤.心脏标志物临床应用进展[M].北京:人民卫生出版社, 2009:98-103.
[4]	Moammar M Q, Ali M I, Mahmood M A, et al.Cardiac troponin Ilevels and alveolar-arterial oxygen gradient in patients with community-acquired Pneumonia[J].Heaet Lung Circ, 2010, l9(2):90-92.
[5]	马健.心肌型脂肪酸结合蛋白对早期诊断心肌损伤的意义探讨[J].临床和实验医学杂志, 2012, 11(19):1535-1536.
[6]	郎宇璜, 缪京丰.心肌型脂肪酸结合蛋白和Myo/H-FABP比值在诊断创伤后心肌损伤中的临床意义[J].创伤外科杂志, 2009, 11(3):237-240.
[7]	彭朋, 薄海, 张磊.肌红蛋白基因多态性与运动性肌肉损伤的相关性[J].武警医学, 2013, 24(2):97-100.
[8]	刘吉福. 胸部钝性创伤中值得关注的几个问题[J].中华外科杂志, 2007, 45(22):1518-1520.