血清心型脂肪酸结合蛋白对非ST段抬高急性冠脉综合征

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Abstract Objective To study the diagnostic value of serum heart-type fatty-acid binding protein(H-FABP)for non-ST-elevation acute coronary syndromes(NSTE ACS). Methods H-FABP and cTnI were measured and compared in 115 NSTE ACS patients and 69 non-cardiac chest pain patients. Results The H-FABP levels were (459±312) pg/ml, (237±169) pg/ml in NSTE ACS group and non-cardiac chest pain group respectively, and there was a significant difference between the two groups(P＜0.05).In NSTE ACS group, the H-FABP level of UAP group was (340±285) pg/ml which was lower than NSTE AMI group (592±289) pg/ml, and there was a significant difference between the two groups(P＜0.05). For the diagnosed NSTE AMI, the area under the ROC curve of H-FABP was 0.863, the sensitivity was 97.1%, specificity was 47.6%; while for the cTnI were 0.799, 61.2%, 93.9%.Conclusions H-FABP is a highly sensitivie marker of the early NSTE ACS and H-FABP detection is conducive to diagnosis of NSTE ACS.

Key words： non-ST-elevation acute coronary syndrome heart-type fatty-acid binding protein

Received: 09 September 2014

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	Articles by authors
	YU Hongbo
	LIU Yang
	LUO Junqing
	LIU Xinguo
	JIAN Ming
	HUANG Meiliang
	LUO Dan
	LI Xuefeng

Cite this article:

YU Hongbo,LIU Yang,LUO Junqing等. Diagnostic value of heart-type fatty-acid binding protein in serum for non-ST-elevation acute coronary syndromes[J]. Med. J. Chin. Peop. Armed Poli. Forc., 2015, 26(2): 133-135.

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http://journal08.magtechjournal.com/Jwk_wjyx/EN/ OR http://journal08.magtechjournal.com/Jwk_wjyx/EN/Y2015/V26/I2/133

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