血管性帕金森综合征与帕金森病的临床特点与影像学特征比较

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Abstract Objective To compare vascular Parkinson’s syndrome and Parkinson’s disease characterized by clinical features and imaging.Methods In department of Neurology in this hospital from December 2010 to August 2014 a total of 70 patients with VP were ascribed to VP group; in the same period in this hospital, 70 patients with Parkinson’s disease were ascribed to Parkinson’s disease group (PD group) . (1) We recorded the two groups’ medical history (hypertension, coronary heart disease, high fat cholesterol, diabetes, stroke), clinical manifestations and symptoms (resting tremor, difficulty in walking, unsteady gait, gait panic, lateral somatosensory disorders). (2) The changes in neuroimaging were observed.Results VP group and PD group had hypertension, coronary heart disease, high fat cholesterol, diabetes, stroke (46%、52%、54%、40%、57%,respectively) and (30%、27%、28%、22%、38%,respectively), the difference was statistically significant (P<0.05).The symptoms in Parkinson’s disease group were mainly resting tremor, the difference between PD and VP group was statistically significant (P<0.05); and the main symptoms in VP patients were difficulty in walking and unsteady gait , compared with the Parkinson’s disease group, the difference was statistically significant (P<0.05).In VP group, the number of senile brain changes and cerebral infarction were significantly more in number than in Parkinson’s disease group, the difference was statistically significant (P<0.05). Conclusions Hypertension, coronary heart disease, high fat cholesterol, diabetes, and stroke, are risk factors for vascular Parkinson’s syndrome. The clinical symptoms and imaging changes of VP are different from those of PD.

Key words： vascular Parkinson’s syndrome Parkinson’s disease clinical features imaging

Received: 05 February 2015

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	QI Jiangtong
	ZHA Caobing
	CHEN Weiliang
	JIN Haijia
	XU Lei

Cite this article:

QI Jiangtong,ZHA Caobing,CHEN Weiliang等. Comparison of vascular Parkinson’s syndrome and Parkinson disease[J]. Med. J. Chin. Peop. Armed Poli. Forc., 2015, 26(6): 545-547.

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http://journal08.magtechjournal.com/Jwk_wjyx/EN/ OR http://journal08.magtechjournal.com/Jwk_wjyx/EN/Y2015/V26/I6/545

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