益生菌用于重度急性胰腺炎治疗的Meta分析

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Abstract Objective To use method of the meta-analysis for evaluating efficacy of probiotics applied to severe acute pancreatitis. Methods The PubMed, The Cochrane Library, CBM database, VIP database, CNKI database, and Wanfang database were searched, comprehensive literature search of the probiotics usage in the treatment of severe acute pancreatitis, and the methodological quality of literatures was evaluated. RevMan 5.0 software was used to conduct statistics and analysis. Results The study participants included 7 articles, a total of 654 patients with severe acute pancreatitis. There were no statistically significant differences in mortality (RR=1.29, 95%CI:0.77-2.16,P=0.33), multiple organ failure incidence (RR=0.81, 95%CI:0.52-1.24,P=0.33), infectious complications incidence(RR=0.72, 95%CI:0.37-1.39,P=0.33)and antibiotics usage(RR=0.89, 95% CI:0.71-1.10,P=0.28)between experimental group and control group. But there was significant statistical difference in pancreatic abscess incidence(RR=0.53, 95%CI:0.28-0.98,P=0.04). Conclusions According to the current research data, probiotics in SAP patients have no positive effects on mortality,multiple organ failure incidence, infectious complications incidence and antibiotics usage. But they can reduce the incidence of pancreatic abscess.

Key words： probiotics severe acute pancreatitis efficacy meta analysis

Received: 20 January 2015

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	NIU Tiantian
	TANG Hongwei

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NIU Tiantian,TANG Hongwei. Meta-analysis of efficacy of probiotics for severe acute pancreatitis[J]. Med. J. Chin. Peop. Armed Poli. Forc., 2015, 26(6): 576-579.

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http://journal08.magtechjournal.com/Jwk_wjyx/EN/ OR http://journal08.magtechjournal.com/Jwk_wjyx/EN/Y2015/V26/I6/576

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