阿奇霉素联合头孢唑肟治疗老年重症社区获得性肺炎合并心力衰竭的疗效

Abstract
Figure/Table
References
Related Citation (15)

Download: PDF (753 KB) HTML (1 KB)
Export: BibTeX | EndNote (RIS)

Abstract Objective To study the clinical curative effect of azithromycin combined with ceftizoxime on treatment of elderly patients with severe community acquired pneumonia and heart failure. Methods The objects of study were 80 elderly patients with severe acquired pneumonia complicated with heart failure who were divided into control group and observation group with 40 cases in each group; the control group used ceftizoxime intervention treatment, the observation group used azithromycin combined with ceftizoxime therapy; and then treatment effect on the two groups of patients was observed . Results The effective rate in, the observation group was 90%,higher than 70% in the control group; the difference was statistically significant (P<0.05).The incidence rate of adverse reaction was 25% in observation group higher than 20% in the control group, the difference was not statistically significant.Conclusions The azithromycin and ceftizoxime used in the elderly patients with severe community acquired pneumonia and heart failure can improve the treatment efficiency, lower BNP, boost LVEF,and does not increase the incidence of adverse events. It is found to be safe and effective, worthy to be recommended.

Key words： Azithromycin ceftizoxime community acquired pneumonia elderly patients with severe heart failure

Received: 22 December 2014

ZTFLH:

R541.1

	Service

	E-mail this article
	Add to my bookshelf
	Add to citation manager
	E-mail Alert
	RSS
	Articles by authors
	CUI Jing
	HUANG Yulian
	WANG Jing

Cite this article:

CUI Jing,HUANG Yulian,WANG Jing. Clinical curative effect of azithromycin combined with ceftizoxime on treatment of elderly patients with severe community acquired pneumonia and heart failure[J]. Med. J. Chin. Peop. Armed Poli. Forc., 2015, 26(7): 659-662.

URL:

http://journal08.magtechjournal.com/Jwk_wjyx/EN/ OR http://journal08.magtechjournal.com/Jwk_wjyx/EN/Y2015/V26/I7/659

[2]	王玉梅, 刘博.复方清金化痰汤联合阿奇霉素治疗老年社区获得性肺炎效果评价[J].社区医学杂志,2014,12(5):1-4.
[1]	吴庆红.阿奇霉素联合头孢他啶治疗社区获得性肺炎的临床观察 [J].中国医药导报,2010,12,36 (7):47-48.
[3]	韩轶,陈继红,李鹏,等.心悦胶囊治疗冠心病慢性充血性心力衰竭气虚血瘀型54例临床疗效观察[J].重庆医科大学学报,2011,36(3):372-374.
[2]	王玉梅, 刘博.复方清金化痰汤联合阿奇霉素治疗老年社区获得性肺炎效果评价[J].社区医学杂志,2014,12(5):1-4.
[4]	吴文梅.阿奇霉素与头孢呋辛治疗社区获得性肺炎的疗效与药品不良反应的对比分析 [J].中国现代药物应用,2011,11(5):58-59.
[3]	韩轶,陈继红,李鹏,等.心悦胶囊治疗冠心病慢性充血性心力衰竭气虚血瘀型54例临床疗效观察[J].重庆医科大学学报,2011,36(3):372-374.
[5]	Florin T A, Ambroggio L. Biomarkers for community-acquired pneumonia in the emergency department[J]. Curr Infect Dis Rep,2014,16(12):451.
[6]	李玉华,朱正林,贾宁宁,等.降钙素原在肺部感染疾病中的应用[J].武警医学,2014,25(2):186-187.
[4]	吴文梅.阿奇霉素与头孢呋辛治疗社区获得性肺炎的疗效与药品不良反应的对比分析 [J].中国现代药物应用,2011,11(5):58-59.
[5]	Florin T A, Ambroggio L. Biomarkers for community-acquired pneumonia in the emergency department[J]. Curr Infect Dis Rep,2014,16(12):451.
[6]	李玉华,朱正林,贾宁宁,等.降钙素原在肺部感染疾病中的应用[J].武警医学,2014,25(2):186-187.
[7]	Alberto C,Pedro P E,Amaia B,et al. Study of community-acquired pneumonia:incidence,patterns of care,and outcomes in primary and hospital care[J]. J Infect,2010,61(5):364-371.
[8]	羿凤云,吴芳,黄汉英,等.综合性医院门诊患者口服新大环内酯类抗生素的处方点评[J].武警医学,2013,24(12):1083-1084.
[7]	Alberto C,Pedro P E,Amaia B,et al. Study of community-acquired pneumonia:incidence,patterns of care,and outcomes in primary and hospital care[J]. J Infect,2010,61(5):364-371.
[8]	羿凤云,吴芳,黄汉英,等.综合性医院门诊患者口服新大环内酯类抗生素的处方点评[J].武警医学,2013,24(12):1083-1084.
[9]	Iroh T P, Hanisch B R, O’Connell M. The impact of adherence to pediatric community-acquired pneumonia guidelines on clinical outcomes[J]. Clin Pediatr (Phila),2014,14(1):157-163.
[10]	杨继龙.阿奇霉素治疗社区获得性肺炎的临床疗效[J].中国保健营养,2013(1):345-346.
[11]	崔娣.不典型肺隐球菌肺炎1例[J].华南国防医学杂志, 2014,28(9):944.
[9]	Iroh T P, Hanisch B R, O’Connell M. The impact of adherence to pediatric community-acquired pneumonia guidelines on clinical outcomes[J]. Clin Pediatr (Phila),2014,14(1):157-163.
[12]	何英姿.阿奇霉素序贯治疗社区获得性肺炎临床效果观察 [J]. 海峡医学,2012,24(2):214-215.
[13]	Kraml P J,Roubalov K ,Bul vas M,et al. Markers of Chlamydia preumoniae and human cytomegalovirus infection in patients with chronic peripheral vascular disease and their relation to inflammation endothelial dysfunction and changes in lipid metabolism [J]. Fo-lia Microbiol,2008,53(6):551-557.
[10]	杨继龙.阿奇霉素治疗社区获得性肺炎的临床疗效[J].中国保健营养,2013(1):345-346.
[14]	Xu S, Xiong S, Xu Y, et al. Efficacy and safety of intravenous moxifloxacin versus cefoperazone with azithromycin in the treatment of community acquired pneumonia[J]. J Huazhong Univ Sci Technolog Med Sci,2006,26(4):421-424.
[11]	崔娣.不典型肺隐球菌肺炎1例[J].华南国防医学杂志, 2014,28(9):944.
[15]	Angel V C,Olga G,Teyesa R B,et al. Epidemiology of commu-nity-acquired pneumonia in older adults.a population-based study [J]. Respir Med,2009,103(2):309-316.
[12]	何英姿.阿奇霉素序贯治疗社区获得性肺炎临床效果观察 [J]. 海峡医学,2012,24(2):214-215.
[13]	Kraml P J,Roubalov K ,Bul vas M,et al. Markers of Chlamydia preumoniae and human cytomegalovirus infection in patients with chronic peripheral vascular disease and their relation to inflammation endothelial dysfunction and changes in lipid metabolism [J]. Fo-lia Microbiol,2008,53(6):551-557.
[14]	Xu S, Xiong S, Xu Y, et al. Efficacy and safety of intravenous moxifloxacin versus cefoperazone with azithromycin in the treatment of community acquired pneumonia[J]. J Huazhong Univ Sci Technolog Med Sci,2006,26(4):421-424.
[15]	Angel V C,Olga G,Teyesa R B,et al. Epidemiology of commu-nity-acquired pneumonia in older adults.a population-based study [J]. Respir Med,2009,103(2):309-316.