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| A study on degeneration of adjacent vertebra after pedicle screw fixation for vertebral fusion |
| KUANG Jingyong1, KUANG Zhengda2 |
1.Xuzhou Medical College, Xuzhou 221004, China;
2. The Third Department of Orthopedics, General Hospital of Chinese People’s Armed Police Forces, Beijing 100039, China |
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Abstract Objective To study the occurrence of adjacent segment degeneration in patients who underwent pedicle screw fixation, and further inquire into the pathogenesis of adjacent segment degeneration. Methods Seventy-two patients with spinal diseases underwent surgical treatment in this hospital from January 2010 to December 2013 were recruited as the study objects, all the patients underwent MRI and X ray examination, the ASD was diagnosed according to the findings of MRI and X-rays, the incidence of ASD was calculated. Visual analog scale (VAS) and Oswestry disability index questionnaire (ODI) were used to assess the pain and functional disability of patients. Results The incidence of ASD was 26.39%. The preoperative pain was significant and a variety of activity functions were affected by pain before the treatment, VAS score was 5.20±1.19, ODI score was 0.43± 0.12. At the last follow-up, VAS score was 2.11±0.82, ODI score was 0.22±0.08, there was statistically significant difference between preoperative and postoperative scores (P<0.05). Conclusions Pedicle screw fixation can induce the occurrence of adjacent segment degeneration. The mechanism may be related to changes of pressure and activity degree of the adjacent segment.
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Received: 24 March 2015
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2015, Vol. 26 
