右美托咪定复合利多卡因雾化吸入用于经鼻清醒气管插管

Abstract
Figure/Table
References
Related Citation (15)

Download: PDF (869 KB) HTML (1 KB)
Export: BibTeX | EndNote (RIS)

Abstract Objective To study the effect of dexmedetomidine combined with nebulized lidocaine inhalation on conscious patients receiving nasotracheal intubation. Methods Ninty conscious patients needing nasotracheal intubation,ASA physical Ⅰ orⅡ,aged 18-60 yr,were randomly divided into three groups (n=30):group D,group L and groupDL.The patients in group D were intravenously administered 1.0 μg/kg dexmedetomidine.The patients in group L inhalated nebulized lidocaine 5 mg/kg.The patients in group DL were intravenously administered 1.0 μg/kg dexmedetomidine combined with nebulized lidocaine 5 mg/kg. Intubation conditions, comfort scores, MAP and HR of basis(T₀) ,before the intubation(T₁), beginning of the intubation(T₂), insertion into the trachea immediately(T₃) and adverse reactions, such as cough, nausea, restless were recorded. The petients were followed up for the memories of intubation after operation. Results Compared with group DL, the intubation conditions and comfort scores were significantly poor in group D and group L. Compared with T₀ and T₁, MAP and HR in group D and group L significantly increased at T₂ and T₃. Compared with group DL, MAP and HR in group D and group L significantly increased at T₂ and T₃. Compared with group D and group DL, the incidence of memory of intubation significantly increased in group L. Conclusions Dexmedetomidine combined with nebulized lidocaine inhalation can inhibit the response of conscious patient receiving nasotracheal intubation.

Key words： difficult airway dexmedetomidine lidocaine conscious intubation response to intubation

Received: 17 March 2015

ZTFLH:

R614.1

	Service

	E-mail this article
	Add to my bookshelf
	Add to citation manager
	E-mail Alert
	RSS
	Articles by authors

Cite this article:

URL:

http://journal08.magtechjournal.com/Jwk_wjyx/EN/ OR http://journal08.magtechjournal.com/Jwk_wjyx/EN/Y2015/V26/I11/1105

[1]	向璟.HC视频喉镜与Macintosh喉镜引导麻醉气管插管的效果比较[J].武警医学,2014,26(12):1193-1195.
[5]	滕永杰,李军,上官王宁,等.利多卡因雾化吸入用于纤维支气镜引导清醒气管插管患者的效果观察 [J] . 临床麻醉学杂志,2011,27 (4):346-348.
[6]	Tsaicj, Chucks,Chenti,et al.A comparison of the effectiveness of dexmedetomidine versus propofol target-controlled infusion for sedation during fibreopticnasotracheal intubation[J]. Anaesthesia,2010,65(3):254-259.
[2]	Shimabukuro A, Satoh K. Airway management with dexmedetomidine for difficult airway. Masui[J]. Anaesthesia, 2007,56(6):681-684.
[7]	Raimr, Parrytm,Dombrovskisa,et al.Remifentanil target-controlled infusion vs propofol target-controlled infusion for conscious sedation for awake fibreoptic intubation:a double-blinded randomized controlled trial[J].Br J Anaesth,2008,100(1):125-130 .
[8]	龙浴辉,胡建军,钟伟强,等. 右旋美托咪啶在清醒镇静纤维支气管镜引导困难气道气管内插管中的应用[J].广东医学,2011,32(17):2287-2288.
[3]	范慧慧,范莹盈,徐浩,等.右美托咪啶用于颌面外科手术清醒纤维支气管镜插管镇静的临床研究[J].实用口腔学杂志,2012,28(2):223-225.
[9]	李荣,方明,张中军.右美托咪定配合表面麻醉在困难气道插管中的应用[J].江苏医药, 2011,37(18):2306-2307.
[4]	柳垂亮,李玉娟,龚文魁,等.右美托咪定用于Shikani喉镜引导颈椎手术清醒气管插管的研究[J]. 国际麻醉学与复苏杂志, 2013,34 (4):293-295.
[10]	方明,李荣,张中军,等.气道黏膜序贯式表面麻醉的清醒气管插管效果[J].江苏医药,2010,36(23):2753-2754.
[5]	滕永杰,李军,上官王宁,等.利多卡因雾化吸入用于纤维支气镜引导清醒气管插管患者的效果观察 [J] . 临床麻醉学杂志,2011,27 (4):346-348.
[11]	Madhere M, Vangura D, Saidov A. Dexmedetomidine as sole agent for awake fiberoptic intubation in a patient with local anesthetic allergy[J]. Anesth, 2011, 25(4): 592-594.
[12]	葛亚丽,郭松青,李倩,等.不同剂量右美托咪定用于高血压患者清醒气管插管的效果[J].临床麻醉学杂志,2013,29 (4):381-383.
[6]	Tsaicj, Chucks,Chenti,et al.A comparison of the effectiveness of dexmedetomidine versus propofol target-controlled infusion for sedation during fibreopticnasotracheal intubation[J]. Anaesthesia,2010,65(3):254-259.
[7]	Raimr, Parrytm,Dombrovskisa,et al.Remifentanil target-controlled infusion vs propofol target-controlled infusion for conscious sedation for awake fibreoptic intubation:a double-blinded randomized controlled trial[J].Br J Anaesth,2008,100(1):125-130 .
[8]	龙浴辉,胡建军,钟伟强,等. 右旋美托咪啶在清醒镇静纤维支气管镜引导困难气道气管内插管中的应用[J].广东医学,2011,32(17):2287-2288.
[9]	李荣,方明,张中军.右美托咪定配合表面麻醉在困难气道插管中的应用[J].江苏医药, 2011,37(18):2306-2307.
[10]	方明,李荣,张中军,等.气道黏膜序贯式表面麻醉的清醒气管插管效果[J].江苏医药,2010,36(23):2753-2754.
[11]	Madhere M, Vangura D, Saidov A. Dexmedetomidine as sole agent for awake fiberoptic intubation in a patient with local anesthetic allergy[J]. Anesth, 2011, 25(4): 592-594.
[12]	葛亚丽,郭松青,李倩,等.不同剂量右美托咪定用于高血压患者清醒气管插管的效果[J].临床麻醉学杂志,2013,29 (4):381-383.