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Effect of high intensity focused ultrasound ablation therapy on uterine myoma |
HU Meili, WANG Yahui, YANG Xin, and WANG Xiaona |
Department of Obstetrics and Gynecology, Baoding Maternity and Children Health Care Hospital, Baoding 071000, China |
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Abstract Objective To observe the clinical effect of treatment on uterine myoma in high intensity focused ultrasound ablation. Methods 74 patients with uterine myoma were treated by high intensity focused ultrasound ablation, treatment effect was observed using a contrast agent, asking discomfort of patients after treatment for 1 week in by phone, following-up, after a month, three months, six months, one-year, improvement of clinical symptoms, while re-examing by ultrasound B, comparatively evaluating treatment results. Results After treatment, clinical manifestations of menorrhagia, urinary frequency, constipation, anemia were improved. Among a total of 76 patients with these symptoms before treatment, one month, three months, six months, 12 months after treatment, 51 cases, 63 cases, 72 cases, 75 cases improved, with average improvement rates of 67.1%, 82.9 %, 94.7%, 98.7%. After three months, six months, 12 months, uterine fibroid volume gradually reduced, medians were 38.43(49.64), 23.07(35.70), 11.67(12.63) cm3, respectively, compared with before treatment, the differences were statistically significant (Z values were 7.391, 7.424, 7.424, P<0.01); Comparing 6 months, 12 months with 3 months after treatment respectively, the difference was statistically significant(P<0.01). Comparing 12 months with six months, uterine fibroid volume little changed, the difference was not statistically significant. Conclusions High intensity focused ultrasound ablation technique can significantly reduce the tumor volume, clinical symptoms improved significantly, it is a safe and effective ideal way to conserve uterus and cure uterine myoma.
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Received: 05 June 2015
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[1] |
谢 辛,苟文丽.妇产科学[M].8版.北京:人民卫生出版社,2014:310-312.
|
[2] |
祝宝让,杨武威,李 静,等.高强度聚焦超声消融子宫肌瘤疗效相关因素分析[J].中华临床医师杂志(电子版),2012,6(2):374-4377.
|
[3] |
Funaki K, Fukunishi H, Sawada K. Clinical outcomes of magnetic resonance-guided focused ultrasound surgery for uterine myomas: 24-month follow-up[J]. Ultrasound Obstet Gynecol, 2009, 34(5): 584-589.
|
[4] |
Wang W, Wang Y, Wang T, et al. Safety and efficacy of US guided high-intensity focused ultrasound for treatment of submucosal fibroids [J]. Eur Radiol, 2012, 22(11): 2553-2558.
|
[5] |
Spies J B, Coyne K, Guaou Guaou N, et al. The UFS-QOL, a new disease-specific symptom and health-related quality of life questionnaire for leiomyomata [J]. Obstet Gynecol, 2002, 99(2): 290-300.
|
[6] |
王丽萍,翁亚娟,王亚金.高强度聚焦超声在子宫腺肌症治疗中的价值[J].陕西医学杂志,2012,41(10):1318-1319.
|
[7] |
侯 静,刘 晟,梁 琪,等.超声引导高强度聚焦超声治疗肌壁间子宫肌瘤的效果[J].中国介入影像与治疗,2013,10(4): 226-229.
|
[8] |
姜 曼,赵 卫,姚瑞红.高强度聚焦超声消融治疗子宫肌瘤的临床应用[J].介入放射学杂志,2013,22(1):82-85.
|
[9] |
汪 伟,刘文英,周洁敏,等. 高强度聚焦超声治疗症状性子宫肌瘤的初步研究[J].中华超声影像学杂志,2002,11(3): 161-163.
|
[10] |
刘映江,刘仙明,彭 松,等.常规MRI在子宫肌瘤超声消融疗效评价及随访中的价值[J].中国医学影像技术,2011,27(10):2098-2101.
|
[11] |
彭 松,黎克全,吴庆蓉,等.影响子宫肌瘤患者接受超声消融治疗相关因素的初步分析[J].重庆医科大学学报,2011,36(12):1460-1463.
|
[12] |
毛赛平,邓新粮.超声消融治疗子宫腺肌病疗效及病例筛选影响因素分析[J].中国实用妇科与产科杂志,2014,30(3): 220-223.
|
|
|
|