空间爬行运动训练对脑缺血幼鼠心理行为的影响

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Abstract Objective To investigate the psychological behavior effects of space creep exercise training for early age cerebral ischemia rats. Methods 59 neonatal rats were randomly divided into 3 groups, 20 in control group with only the neck skin incision and suture, without bilateral common carotid artery ligation; 20 in cerebral ischemia group with bilateral common carotid artery ligation ; 19 in cerebral ischemic exercise group , 4 days after bilateral common carotid artery ligation, given a 4 weeks creep space exercise training with homemade exercise rack. Control group and cerebral ischemia group did not receive exercise training. The Animal Behaviour Science Platform (Scotch instrument and open-field test) was used to measure the movement and behavior of these 38-40 days old rats. Results (1) The landing incubation period in cerebral ischemic exercise group and the control group was much longer than in cerebral ischemia group (t=4.159, P＜0.01; t=4.696, P＜0.01), while the control group and cerebral ischemia exercise group had no significant difference (t=1.418). (2) In the open field test, 3 groups had no significant difference in the total distance and average speed (all P＞0.05). (3) Peripheral activity time and distance in cerebral ischemic exercise group and the control group were much longer than in cerebral ischemia group (t=4.848, P＜0.001, t=6.583, P＜0.001; t=2.764, P＜0.05, t=3.988, P＜0.01; t=3.102, P＜0.05, t=3.258,P＜0.05) , while the number of cross-grid times, peripheral activity time and distance between the control group and cerebral ischemic exercise group had no significant difference. (4) Center activity time and distance in cerebral ischemic exercise group and the control were was much shorter than in cerebral ischemia group (t=4.881, P＜0.01; t=3.533, P＜0.01; t=3.783, P＜0.01, t=3.142, P＜0.05), while the cerebral ischemic exercise group and the control group had no dignificent difference. Conclusion For the cerebral ischemia rats, movement and behavior state are impaired, early space creeping exercise training can significantly improve the movement, coordination and cognitive abilities.

Key words： space creep behavior cerebral ischemia medical psychology rat

Received: 02 May 2015

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	Articles by authors
	WANG Yali
	QI Jingtong
	DU Kaiqi
	ZHANG Jinlong
	CHEN Guojun
	MA Yuhai
	and LIU Qiuling

Cite this article:

WANG Yali,QI Jingtong,DU Kaiqi等. Psychological behavior effects of space creep exercise training for early age cerebral ischemia rats[J]. Med. J. Chin. Peop. Armed Poli. Forc., 2015, 26(11): 1145-1148.

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http://journal08.magtechjournal.com/Jwk_wjyx/EN/ OR http://journal08.magtechjournal.com/Jwk_wjyx/EN/Y2015/V26/I11/1145

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