|
|
Clinical observation of double plasma exchange in liver transplantation in ABO blood group incompatibility |
TIAN Eryun1,GONG Jingping2,YIN Lihua1,and XIANG Xueyuan1 |
1.Comprehensive Building Intensive Care Medicine, 2. Department of Nursing,General Hospital of Chinese People’s Armed Police Force. Beijing 100039 ,China |
|
|
Abstract Objective To investigate the therapeutic effect of double plasma exchange in the treatment of ABO incompatible liver transplantation. Methods The clinical data of 20 cases of ABO incompatible liver transplantation in this hospital were retrospectively analyzed were observed in double plasma exchange group and control group after 3 weeks of treatment. Illness prognosis was followed up after treatment for 3 months and influencing factors were analyzed. Results According to the laboratory test, after double plasma exchange treatment for 24 hours, 5 patients with receptor preoperative blood group antibody titer of 1∶32 showed stability in 1∶8 within 24 hours after the operation; 3 patients with receptor preoperative blood group antibody titer of 1∶4 showed: stablitg in 1∶2 within 7 days after the operation; 2 patients with reseptor of 1∶16, began to rebound after 2-3 months and then decreased and stabliized in 1∶8. According to the overall effect, in the treatment group of 10 patients, 8 cases were effective, an effective rate of 80%. In the control group, 10 cases (4) were effective, 5 cases (40%), 1 cases (10%) were discharged. The efficacy in the treatment group was significantly higher than that in the control group (P<0.05). Conclusions Double plasma exchange is an effective and reliable technique for the treatment of different liver transplantation, which can improve the survival time of patients.
|
Received: 05 June 2015
|
|
|
|
|
[1] |
Egawa H, Ohdan H, Haga H, et al.Current status of liver transplantation across ABO blood-type barrier[J]. J Hepatobiliary Pancreat Surg, 2008,15: 131.
|
[1] |
Egawa H, Ohdan H, Haga H, et al.Current status of liver transplantation across ABO blood-type barrier[J]. J Hepatobiliary Pancreat Surg, 2008,15: 131.
|
[2] |
苏春雄,雷任国,兰玲鲜,等.双重血浆分子吸附术治疗肝衰竭的疗效观察[J].广西医科大学学报,2014,31(5):818-820.
|
[2] |
苏春雄,雷任国,兰玲鲜,等.双重血浆分子吸附术治疗肝衰竭的疗效观察[J].广西医科大学学报,2014,31(5):818-820.
|
[3] |
刘其雨,李 立, 李晓延.ABO血型不合肝移植的研究进展[J].中国普外基础与临床杂志,2009,16(3):195-198.
|
[3] |
刘其雨,李 立, 李晓延.ABO血型不合肝移植的研究进展[J].中国普外基础与临床杂志,2009,16(3):195-198.
|
[4] |
阎 冰,李 捷,郭文治.ABO血型不合肝移植术后急性抗体介导的排斥反应研究进展[J].中华肝脏外科手术学电子杂志,2014,3(2):124-126.
|
[4] |
阎 冰,李 捷,郭文治.ABO血型不合肝移植术后急性抗体介导的排斥反应研究进展[J].中华肝脏外科手术学电子杂志,2014,3(2):124-126.
|
[5] |
王英杰.人工肝在肝衰竭中的应用与评价[J].实用肝脏病杂志,2013,16(1):20-21.
|
[6] |
Gong D,Ji D,Xu B, et al. More selective removal of myeloperoxidaseanti- neutrophil cytoplasmic antibody from the circulation of patients with vasculitides using a novel double-filtration plasmapheresis therapy[J].Ther Apher Dial,2013,17(1):93-98.
|
[5] |
王英杰.人工肝在肝衰竭中的应用与评价[J].实用肝脏病杂志,2013,16(1):20-21.
|
[7] |
Matsuno N, Nakamura Y, Mejit A, et al. Long-term follow-up ABO-incompatible adult living donor liver transplantation in cirrhotic patients[J]. Clin Transplant, 2007,21:638.
|
[6] |
Gong D,Ji D,Xu B, et al. More selective removal of myeloperoxidaseanti- neutrophil cytoplasmic antibody from the circulation of patients with vasculitides using a novel double-filtration plasmapheresis therapy[J].Ther Apher Dial,2013,17(1):93-98.
|
[8] |
林建华,周 杰,张起帆. ABO血型不相容肝移植的可行性[J].中国组织工程研究与临床康复,2010,15(44):25-29.
|
[7] |
Matsuno N, Nakamura Y, Mejit A, et al. Long-term follow-up ABO-incompatible adult living donor liver transplantation in cirrhotic patients[J]. Clin Transplant, 2007,21:638.
|
[8] |
林建华,周 杰,张起帆. ABO血型不相容肝移植的可行性[J].中国组织工程研究与临床康复,2010,15(44):25-29.
|
|
|
|