恶性肿瘤患者凝血指标浓度变化特点分析

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Abstract Objective To study the characteristics of blood coagulation index concentration change in tumor patients. Methods 115 cancer pationts were divided into groups of stomach cancer, colon cance and lung cancer. For the patients, the levels of blood clotting index before and after chemotherapy coagulation index changes over time were detected and blood coagulation indexes were detected in 50 cases of control group. Results In patients with cancer, plasma prothrombin time (PT) (12.39±1.23)s, activated partial thromboplastin time (APTT) (30.58±7.43)s, fibrinogen (FIB) (4.71±1.72)g/L, D- dimer (D-Dimer) (1.32±0.16 )μg/ml levels were significantly higher than in the control group (P<0.05). In patients with different types of tumor plasma PT, APTT, FIB, D-Dimer levels were significantly higher than in the control group (P<0.05). In lung cancer group, plasma FIB level was significantly higher than in colorectal cancer group and gastric cancer group (P<0.05). The plasma FIB level in gastric cancer group and colorectal cancer group was not significantly different. In gastric cancer group, lung cancer group and colorectal cancer group, plasma FIB levels did not obviously change in different periods of chemotherapy. Conclusions Coagulation indices for tumor diagnosis and curative effect monitoring have some help and are good indicators to excluded tumor, and preven venous thrombosis.

Key words： cancer chemotherapy coagulation indicators

Received: 11 May 2015

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	Articles by authors
	WANG Huifang
	YU Caixia
	WANG Jiapo
	WANG Guozeng
	ZHANG Shuo
	WANG Lili
	LI Lixia
	ZhuLili
	and KUANG Tieji

Cite this article:

WANG Huifang,YU Caixia,WANG Jiapo等. Clinical analysis of routine blood coagulation index concentration change in 115 cancer patients[J]. Med. J. Chin. Peop. Armed Poli. Forc., 2016, 27(1): 26-28.

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http://journal08.magtechjournal.com/Jwk_wjyx/EN/ OR http://journal08.magtechjournal.com/Jwk_wjyx/EN/Y2016/V27/I1/26

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