大量输血对受血者凝血功能的影响

Abstract
Figure/Table
References
Related Citation (5)

Download: PDF (588 KB) HTML (1 KB)
Export: BibTeX | EndNote (RIS)

Abstract Objective To study the effects of massive blood transfusion on coagulation function in blood recipients.Methods Clinical data of 85 massive transfusion patients (≥1200 mL) admitted from January 2012 to May 2015 were reviewed retrospectively.Items of blood routine test (HGB, HCT, PLT etc.) and blood coagulation test (HGB, HCT, PLT, etc.) at preoperative time, 1st day and 3rd day of postoperation were measured, collected and analyzed separately.Results Postoperative PLT level significantly decreased,compared with that of pre-operation; and did not restore to preoperative levels even 3 days after operation, the difference was statistically significant (P<0.05). HCT and HGB levels at the 1 st postoperative day were significantly higher than those pre-operation, the difference was statistically significant (P<0.05). HCT and HGB at the 3rd postoperative day were higher than those pre-operation. FIB level at the 1st postoperative day was significantly lower than that pre-operation, the difference was statistically significant (P<0.05). FIB level at the 3rd postoperative day was higher than that pre-operation, the difference was statistically significant (P<0.05). PT, TT, APTT at the 1st postoperative day were longer than those pre-operation, the difference was statistically significant (P<0.05). PT, TT, APTT at the 3rd postoperative day were significantly improved, compared with those at the 1st postoperative day, the difference was statistically significant (P<0.05).Conclusions The platelet level in blood recipient reduces significatly after massive transfusion, and the coagulation function decreases greatly.Coagulation function should be monitored closely to aware the occueernce of its dysfunction.

Key words： blood recipient coagulation function massive transfusion

Received: 11 October 2015

ZTFLH:

R457.1

	Service

	E-mail this article
	Add to my bookshelf
	Add to citation manager
	E-mail Alert
	RSS
	Articles by authors
	ZHANG Ying
	REN Huiyan
	and ZHENG Yanrong

Cite this article:

ZHANG Ying,REN Huiyan,and ZHENG Yanrong. Effects of massive blood transfusion on coagulation function in blood recipients[J]. Med. J. Chin. Peop. Armed Poli. Forc., 2016, 27(4): 353-355.

URL:

http://journal08.magtechjournal.com/Jwk_wjyx/EN/ OR http://journal08.magtechjournal.com/Jwk_wjyx/EN/Y2016/V27/I4/353

[1]	袁杰,石天,罗艳.多次大量输血对老年患者凝血功能的影响[J].中国老年学杂志,2013,33(1):207-208.
[2]	大量输血现状调研协作组.全国多中心大量输血凝血值调研分析[J].中国输血杂志,2012,25(7):632-635.
[3]	Como J J, Dutton R P, Scalea T M, et al. Blood transfusion use rates in the care of acute trauma[J].Transfusion, 2004,6(44):809-809.
[4]	王同显,马保凤.严重创伤患者大量输血的研究进展[J].中国输血杂志,2012,25(7):636-638.
[5]	韩杰,李春华.大量输血对患者血小板和凝血功能的影响[J].北京医学,2011,33(10):860-861.
[6]	叶一冰,秦杰,李方顺,等.大量成分输血在抢救严重创伤大出血患者中的临床效果分析[J].中国医师进修杂志,2012,35(20):66-67.
[7]	吴小梅.血浆与红细胞不同比例输注对大量输血患者凝血功能的影响[J].国际检验医学杂志,2014,4(11):435-436.
[8]	刘芬,汪泱,詹以安.大量输血时血浆与浓缩红细胞不同比例输注对产后大出血患者凝血功能的影响[J].实用医学杂志,2010,12(6):1000-1002.
[9]	Meyer M A S,Ostrowski S R,Windel N A,et al. Fibrinogen concentrates for bleeding trauma patients: what is the evidence [J].Vox Sang,2011,101(3):185-190.
[10]	Sinha R Roxby D. Transfusion practices in massive haemorrhage in preintensive and intensive care[J]. Vox Sanguinis,2011,101(3):230-236.
[11]	周洁,吕科,滕方.血浆与红细胞不同输注比例对创伤性失血患者大量输血救治的影响[J].中国输血杂志,2011,24(10):844-847.