持续气道正压通气对冠心病合并阻塞性睡眠呼吸暂停患者血压和昼间嗜睡的干预效果

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Abstract Objective To study the effect of CPAP (continuous positive airway pressure) on the blood pressure of patients with coronary heart disease combined with obstructive sleep apnea (OSA) and daytime sleepiness.Methods 160 patients with coronary heart disease combined with OSA were randomly divided into study group (medication combined with CPAP treatment) and control group (medication treatment). There were 80 cases in each group. The blood pressure, Epworth sleepiness scale (ESS score) and the change of multiple sleep latency test (MSLT) were observed.Results Before the treatment, there were no significant differences in the blood pressure level, ESS score and MSLT test Results between the two groups. After the treatment, the blood pressure levels significantly decreased in two groups. In the study group after treatment, the average systolic blood pressure (24 h-MDBP), 24 h average diastolic blood pressure (24 h-MSBP), the average systolic blood pressure (dMSBP) during the day, the average diastolic blood pressure (dMDBP) during the day, the average night systolic blood pressure (nMSBP) and average diastolic blood pressure at night (nMDBP) were:(130.8±11.9)mmHg,(85.5±2.9)mmHg,(131.9±10.2)mmHg,(86.1±3.5)mmHg,(128.4±18.66) mmHg,and(83.7±4.1)mmHg, there were significant differences(P<0.05). The effect, in the study group one month and three months after the treatment were better than in the control group,there were significant differences(P<0.05).Conclusions CPAP can improve the blood pressure in the patients with coronary heart disease and OSA and daytime sleepiness.

Key words： CPAP coronary heart disease obstructive sleep apnea blood pressure daytime sleepiness

Received: 24 November 2015

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	Articles by authors
	SU Hong
	ZHAO Yueping
	ZHU Hongxia
	SUN Xiaoxue
	SUN Mengmeng
	WU Lei
	ZHANG Yue
	and YUAN Feiyang

Cite this article:

SU Hong,ZHAO Yueping,ZHU Hongxia等. Effect of continuous positive airway pressure on blood pressure of patients with coronary heart disease combined with obstructive sleep apnea (OSA) and daytime sleepiness[J]. Med. J. Chin. Peop. Armed Poli. Forc., 2016, 27(4): 389-391.

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http://journal08.magtechjournal.com/Jwk_wjyx/EN/ OR http://journal08.magtechjournal.com/Jwk_wjyx/EN/Y2016/V27/I4/389

[1]	Bamberga M,Rizzi M,Gadaleta F,et al.Relationship between energy expenditure, physical activity and weight loss during CPAP treatment in obese OSA subjects[J].Respir Med,2015,109(4):540-545.
[2]	刘建伟,刘松,李雪峰,等.中重度阻塞性睡眠呼吸暂停低通气综合征患者白天过度嗜睡与持续气道正压治疗依从性的关系[J].中国全科医学,2012,15(26):2993-2995.
[3]	Chan K,Cossa G,Birring S,et al.Impact of continuous positive airway pressure (CPAP) on chronic cough in obstructive sleep apnoea (OSA) - A randomized controlled trial[J].Sleep Med,2013,14(3):e95.
[4]	慈书平,戴煌,倪竟全,等.阻塞性睡眠呼吸暂停综合征与高脂血症关系长期随访研究[J].中国临床医生,2013,41(7):20-22.
[5]	中华医学会呼吸病学分会睡眠呼吸障碍学组.阻塞性睡眠呼吸暂停低通气综合征诊治指南(2011年修订版)[J].中华结核和呼吸杂志,2012,35(1):9-12.
[6]	Anil A,Monali P,Morohunfolu A,et al.Cardiovascular mortality in obstructive sleep apnoea treated with continuous positive airway pressure or oral appliance:an observational study[J].Respirology,2013,18(8):1184-1190.
[7]	Millichamp K A,Vicky C,Syed A A.Immediate changes in continuous positive airway pressure after bariatric surgery in obese people with obstructive sleep apnoea[J]. Eur J Intern Med,2014,25(3):e33-e34.
[8]	聂晓敏,苏利霄,周雅婧,等.大蒜素对冠心病合并阻塞性睡眠呼吸暂停低通气综合征患者血管内皮功能的影响[J].中华医学杂志,2014,94(28):2184-2187.
[9]	姬月华,陆华东.阻塞性睡眠呼吸暂停低通气综合征合并稳定型冠心病患者采用持续正压通气治疗时心功能变化的研究[J].中国现代医生杂志,2014,52(32):13-15.
[10]	Gagnadoux F,Le VM,Paris A, et al.Adherence to positive airway pressure in non-sleepy patients with obstructive sleep apnoea.[J]. Eur Respir J,2013,42(3):863-866.
[11]	廖小雯,张亦飞,汤玉蓉.持续正压通气呼吸机在阻塞性睡眠呼吸暂停综合征治疗中的应用[J].中外医学研究,2014,12(23):44-45.
[12]	Wilczynska M,Rice S,Davies G,et al. Endothelial injury markers before and after nasal continuous positive airway pressure treatment for obstructive sleep apnoea hypopnoea syndrome.[J].Sleep Breath,2014,18(3):599-607.
[13]	周波,杨皖菁.阻塞性睡眠呼吸暂停低通气综合征患者持续正压通气治疗后脂代谢及血清瘦素水平变化分析[J].中华临床医师杂志(电子版),2013,7(24):11848-11851.
[14]	赵青,柳志红,罗勤,等.持续气道正压通气对冠心病合并阻塞性睡眠呼吸暂停患者血压和昼间嗜睡的影响[J].中国循环杂志,2013,27(5):111-112.