eIF4E生物学功能及其在肿瘤中作用研究进展

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[1]	Weinstein I B,Joe A.Oncogene addiction [J].Cancer Res,2008,68(9):3077-3080.
[2]	Solimini N L,Luo J,Elledge S J.Nononcogene addiction and the stress phenotype of cancer cells [J].Cell,2007,130(6):986-988.
[3]	Joshi B,Cameron A,Jagus R.Characterization of mammalian eIF4E-family members[J].Eur J Biochem,2004,271(11):2189-2203.
[4]	Jackson R J,Hellen C.U,Pestova T V.The mechanism of eukaryotic translation initiation and principles of its regulation[J].Nat Rev Mol Cell Biol,2010,11(2):113-127.
[5]	Sonenberg N, Hinnebusch A G..Regulation of translation initiation in eukaryotes:mechanisms and biological targets[J].Cell,2009,136(4):731-745.
[6]	Schwanhausser B,Baunse D,Li N,et al.Global quatification of mammalian gene expression control [J].Nature,2011,473(7347):337-342.
[7]	Bergman J E,Lodish H F,A kinetic model of protein synthesis.Application to hemoglobin synthesis and translation control[J].J Biol Chem,1979,254(23):11927-11937.
[8]	Parsyan A,Svitkin Y,Shahbazian D,et al. Mrna helicases:The tacticians of translation control[J].Nat Rev Mol Cell Biol,2011,12(4):235-245
[9]	Graff J R,Konicek B W,Carter J H, et al.Targeting the eukaryotic traslation initiation factor 4E for cancer therapy[J].Cancer Res,2008,68(3):631-634.
[10]	Topisirovic I,Siddiqiu N,Lapointe V L,et al.,Molecular dissection of the enkaryotic initiation factor 4E(eIF4E) export-competent RNP[J].EMBO J,2009,28(8):1087-1098.
[11]	Culjkovic B,Baguet A,Voipon L,et al.The oncogene eIF4E reprograms the nuclear pore complext to promote mRNA export and oncogenic transformation[J].Cell Rep,2012,2(2):207-215.
[12]	Keene J D.RNA regulons:coordination of post-transcriptional events[J].Nat Rev Genet,2007,8(7):533-543.
[13]	Schmidt E V.The role of c-myc in regulation of translation initiation[J].Oncogene,2004,23(18):3217-3221.
[14]	Topisirovic I,Siddiqiu N,Orolicki S,et al.Stablity of eukaryotic translation innitiation factor 4E mRNA is regulated by Hur,and this activity is dysregulated in cancer[J]. Mol Cell Biol,2009,29(5):1152-1162.
[15]	Murata T,Shimotohno K.Ubiquitination and proteasome-dependent degration of human eukaryotic translation innitiation factor 4E[J].J Biol Chem,2006,281(30):20788-20800.
[16]	Pyronnet S.Phosphorylation of the cap;binding protein eIF4E by the MAPK-activated protein kinase Mnk1[J].Biochem Pharmacol,2000,60(8):1237-1243.
[17]	Wendel H G,Silva R L,Malina A,et al.Dissecting eIF4E action in tumorigenesis[J].Genes Dev,2007,21(24):3232-3237.
[18]	Furic L,Rong L,Larsson O,et al. eIF4E phosphorylation promotes tumorigenesis and is associated with prostate cancer progression[J]. Proc Natl Acad Sci,2010, 107(32):14134-14139.
[19]	Dobrikov M, Dobrikova E,Shveygert M,et al. Phosphorylation of eukaryotic translation innitiation factor 4G1(eIF4G1) by protein kinase C〔alpha〕regulates eIF4G1 binding to Mnk1[J].Mol Cell Biol,2011,31(14):2947-2959.
[20]	Orton K C,Ling J,Waskiewicz A J,et al. Phosphorylation of Mnk1 by caspase-activated Pak2/gamma-PAK inhibits phosphorylation and interaction of eIF4G with Mnk[J].J Biol Chem, 2004,279(37):38649-38657.
[21]	Kinkelin K,Veith K,Grunwald M,et al.Crystal structure of a minimal eIF4E -Cup complex reveals a general mechanism of regulaion in translational repression[J].RNA,2012,18(9):1624-1634.
[22]	Tomoo K,Matsushita Y,Fujisaki H,et al.Structure basis for mRNA cap-binding regulation of eukaryotic innitiation factor 4E by 4E-binding protein ,studied by spectroscopic,X-ray crystal structural,and molecular dynamics simulation methods[J].Biochim Biophy Acta,2005,1753(2):191-208.
[23]	Topisirovic I,Culjkovic B,Cohen N,et al.The proline-rich protein,PRH,is a tissue-specific inhibitor of eIF4E-dependent cyclin D1 mRNA transport and growth[J].EMBO J,2003,22(3):689-703.
[24]	Petterson F,Yau C,Dobocan MC,et al.Ribavirian treatment effects on breast cancers oerexpressing eIF4E,a biomarker with prognostic specificity for luminal B-type breast cancer[J].Clin Cancer Res,2011,17(9):2874-2884.
[25]	Li Y,DcFatta R,Anthony C,et al.A translationally regulated Tousled kinase phosphorylates histone H3 and confers radioresistance when overexpressed[J].Oncogene,2001,20(6):726-738
[26]	Lise B,Helene M M,Isabelle G,et al. eIF4E is a nexus of resistance to anti-BRAF and anti-MEK cancer therapies[J].Nature,2014,513(9):105-109.
[27]	Pieere Z,Yann B,Ben A,et al.Formation of the eIF4F translation-initiation complex determines sensitivity to anticancer drugs targeting the EGFR and HER2 receptors[J].Cancer Res,2011,7(12):4068-4073.
[28]	Yikun L,Songqing F,Junghui K,et al.Elevated expression of eukaryotic translation initiation factor 4E is associated with proliferation,invasion and acquired resistance to eelotinib in lung cancer[J].Cancer Biol Ther,2012,13(5):272-280.