|
|
Clinical analysis of seventy-two cases of placental abruption |
LI Xuhong1, WANG Jing2, and SHANG Lixin2 |
1.Department of Gynecology and Obstetrics, Clinical College of Army General Hospital ,Anhui Medical University, Hefei 230032,China; 2.Department of Gynecology and Obstetrics, Army General Hospital,Beijing 100700,China |
|
|
Abstract Objective To explore the factors that influence the outcomes of pregnancy in placental abruption so as to improve the ability of early diagnosis and treatment of placental abruption.Methods The clinical data on seventy-two cases of placental abruption treated at Army General Hospital between January 2010 and January 2016 were retrospectively reviewed. The causes of placental abruption and the influence of hypertensive disorders and standard checkups on pregnancy outcomes were analyzed.Results The severity of placental abruption depended on three important factors: hypertensive disorders in pregnancy, standard checkups and the interval between the onset of the first initial clinical sign and delivery. Severe cases of placental abruption(1-120 h) took a longer time to treat than minor ones(1-51.5 h),and the difference was statistically significant(P<0.05).The incidence of postpartum hemorrhage(38.5%,40.7%), acute kidney injury(11.5%,11.1%), premature birth (70.4%,72.4%)and low birth weight baby (59.3%,68.9%)in cases with gestational hypertension group and non-standard checkup group was significantly higher than in control group (P<0.05).There were four cases of severe placental abruption and all the perinatal infants died.Conclusions We can improve the pregnancy outcome of placental abruption by identifying the causes, standardizing checkups during pregnancy and ensuring early diagnosis and treatment.
|
Received: 29 June 2016
|
|
|
|
|
[1] |
谢 幸,苟文丽.妇产科学 (十二五普通高等教育本科国家级规划教材)[M]. 8版.北京:人民卫生出版社,2013:129-131.
|
[2] |
Martinez-Biarge M, Madero R, González A, et al. Perinatal morbidity and risk of hypoxic-ischemic encephalopathy associated with intrapartum sentinel events[J]. AJOG, 2013, 206(2):1-7.
|
[3] |
丰有吉,沈 铿.妇产科学[M]. 2版.北京:人民卫生出版社,2005:156-165.
|
[4] |
Friedman A M, Cleary K L. Prediction and prevention of ischemic placental disease[J]. Semin Perinatol, 2014, 38(3):177-182.
|
[5] |
Roberts J M. Pathophysiology of ischemic placental disease.[J]. Semin Perinatol,2014,38(3):139-145
|
[6] |
李 磊,连 岩,王谢桐.胎盘缺血与胎盘早剥[J].中国实用妇科与产科杂志,2016,32(4):312-315.
|
[7] |
张丽君.胎盘早剥332例临床分析[J].中国妇幼健康研究,2015,26(1):73-75.
|
[8] |
Brosens I, Pijnenborg R, Vercruysse L, et al. The “Great Obstetrical Syndrome” are associated with disorders of deep placentation[J]. AJOG, 2010, 204(3):193-201.
|
[9] |
Wathén K A, Sarvela J, Stenman F, et al. Changes in serum concentrations of soluble vascular endothelial growth factor receptor-1 after pregnancy[J]. Hum Reprod, 2011, 26(1):221-226.
|
[10] |
王雅楠,杨 孜.影响胎盘早剥临床结局的相关因素及防范策略[J].中国实用妇科与产科杂志,2010,26(2):114-118.
|
[11] |
Kadasne A R, Mirghani H M. The role of ultrasound in life-threatening situations in pregnancy[J]. J Emerg Trauma & Shock, 2011, 4(4):508-510.
|
[12] |
陈 娟,盖铭英.前置胎盘及胎盘早剥的超声诊断[J].实用妇产科杂志,2010,26(7):488-490.
|
[13] |
梁晓萍,陈 玲,吴大保.胎盘早剥保守治疗的临床分析[J].实用妇产科杂志,2013,29(6):457-460.
|
[14] |
徐元春,康 程,王细先,等.重度胎盘早剥的处理时限与妊娠结局[J].中国妇产科临床杂志,2011,12(3):176-179.
|
|
|
|