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| Relationships between oxidative stress, inflammation and ischemic stroke |
| HE Jufang1, LI Tingting2, SUN Xiaoyun3, DONG Mei1, LI Kang1, BAI Guangliang1, ZHANG Lina1, MEI Xue1, and WANG Ruwei1 |
1.Department of Clinical Laboratory,the 309th Hospital of PLA, Beijing 100091, China;
2.Grade 10,Medical Laboratory Speiality,Hebei North Medical University,Zhangjiakou 075000,China;
3.Weigongcun Cadre’s Sanatorium Clinic of the Political Department of the Central Military Commision,Beijing 100081,China |
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Abstract Objective To investigate the diagnostic value of levels of TAC,Ox-LDL,SOD and Hs-CRP of serum for patients with ischemic stroke.Methods The levels of TAC and Ox-LDL were detected by enzyme-linked immunosorbent assay. A Beckman Coulter AU5821 blood biochemical analyzer was used to detect other indexes.Results In the patient group, the level of TAC was decreased significantly, almost 1/12 of the level of the normal control group(P<0.01),and the levels of HDL-C and SOD were also decreased(P<0.05), but the levels of Hs-CRP, Ox-LDL and LDL-C were markedly increased(P<0.01).In the patient group, the level of Hs-CRP was 16 times that of the normal control group, the level of Ox-LDL was 1.7 times the normal level, and the level of LDL-C was 1.6 times the normal level.Conclusions There is significant difference between ischemic stroke patients and normal controls.The occuurence of ischemic stroke is closely related to oxidative stress and inflammation.
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Received: 15 August 2016
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2016, Vol. 27 
