颅咽管瘤显微手术治疗及疗效分析

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Abstract Objective To explore the therapeutic effect of microsurgical methods on craniopharyngioma.Methods The clinical data of 136 cases of patients with craniopharyngioma treated in our hospital between January 2010 and December 2014 were retrospectively analyzed. Operations were performed under the microscope. The the fronto basal interhemispheric approch was adopted in 42 cases,subfrontal approach in 28 cases, callosal interforniceal approach in 27 cases, pterional approach in 36 cases, and the transsphenoidal approach in 3 cases.Results Total tumor removal was achieved in 118 cases, subtotal removal in 14 cases, and partial removal in 4 cases. Also, there were 63 cases of postoperative diabetes insipidus (temporary diabetes insipidus in 42 cases),and 28 cases of decreased vision or blindness. Electrolyte disorders occurred in 65 cases. As for other complications, there were 8 cases of central high fever, 3 cases of oculomotor nerve injury, 1 case of cerebral infarction, 2 cases of intracranial infection. And 3 cases of death one month after operation. There were also 3 cases of automatic discharge, who gave up treatment because of the severity of illness or for financial reasons.Conclusions Selection of an appropriate surgical approach based on the location and growth mode of the craniopharyngioma is the key to the success of surgical treatment.

Key words： craniopharyngioma microsurgery surgical approach

Received: 02 January 2016

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R651.19

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	Articles by authors
	QIN Zhizhen
	WANG Jianzhen
	MA Zhenyu
	DU Changsheng
	LI Zhongming
	FENG Yaohui
	DIAO Jinfu
	XING Jian

Cite this article:

QIN Zhizhen,WANG Jianzhen,MA Zhenyu等. Microsurgical treatment and efficacy of patients with craniopharyngioma[J]. Med. J. Chin. Peop. Armed Poli. Forc., 2017, 28(1): 51-53.

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http://journal08.magtechjournal.com/Jwk_wjyx/EN/ OR http://journal08.magtechjournal.com/Jwk_wjyx/EN/Y2017/V28/I1/51

[1]	王忠诚.王忠诚神经外科学[M].武汉:湖北科学技术出版社,2005:659-660.
[2]	Garnett M R,Puget S,Grill J,et al.Craniopharyngioma[J].Orphanet J Rare Dis,2007,2:18.
[3]	戴平丰,胡吉波,周晓俊,等.颅咽管瘤的 MRI信号模式[J].临床放射学杂志,2002,21(4):260-263.
[4]	符有文,罗泽斌.实性颅咽管瘤的 CT和 MRI诊断[J].现代医学影像学,2006,15(2):64.
[5]	Yasargil M G,Curcic M,Kis M,et al.Total removal of craniopharyngiomas.Approaches and longterm results in 144 patients[J].J Neurosurg,1990,73(1):3-11.
[6]	Vinchon M,Dhellemmes P.Craniopharyngiomas in children: recurrence,reoperation and outcome[J].Childs Nerv Syst,2008,24(2):211-217.
[7]	Shi X E,Wu B,Fan T,et al.Craniopharyngioma:Surgical experience of 309 cases in China[J].Clin Neurol Neuro-surg,2008,110(2):151-159.
[8]	Kawamata T,Amano K,Aihara Y,et al. Optimal treatment strategy for craniopharyngiomas based on long-term functional outcomes of recent and past treatment modalities[J].Neurosurg Rev,2010,33(1):71-81.
[9]	Komotar R J,Roguski M,Bruce J N.Surgical management of craniopharyngiomas[J].J Neurooncol,2009,92(3):283-296.
[10]	Honegger J,Tatagiba M.Craniopharyngioma surgery[J].Pituitary,2008,11(4):361-373.
[11]	Zuccaro G.Radical resection of craniopharyngioma[J].Childs Nerv Syst,2005,21(8-9):679-690.
[12]	雷霆,舒凯,韩林,等.经蝶窦入路显微手术切除颅咽管瘤[J].中华神经外科杂志,2008,24(7):493-495.
[13]	Hassaneen W,Suki D,Salaskar A L,et al.Immediate morbidity and mortality associated with transcallosal resection of tumors of the third ventricle[J].J Clin Neuro-sci,2010,17(7):830-836.
[14]	Frank G,Pasquini E,Doglietto F,et al.The endoscopic extended transsphenoidal approach for craniopharyngiomas[J].Neurosurgery,2006,59(1 Suppl 1):75-83.
[15]	范虹,钟历勇,刘巍,等.颅咽管瘤术后脑性盐耗综合征67例临床分析[J].临床内科杂志,2008,25(5):356.
[16]	张礼均,冯华.严重神经外科疾患引起低钠血症[J].国际神经病学神经外科学杂志,2005,32(4):358-362.
[17]	郑细良,张玉琪.颅咽管瘤术后激素替代治疗[J].中华神经外科杂志,2006,22(2):127-129.
[18]	Chakrabarti I,Amar A P,Couldwell W,et al.Long-term neurological,visual,and endocrine outcomes following transnasal resection of craniopharyngioma[J].J Neurosurg,2005,102(4):650-657.
[19]	李蓉,管晓萍,任红丽,等.针对性健康教育对颅内肿瘤患者家属焦虑状况的影响[J].中国急救复苏与灾害医学杂志,2014,9(7):633-635.
[20]	李冬梅,赵海萍,韩玉婷,等.小儿颅咽管瘤31例围手术期护理[J].武警医学,2014,25(10):1071-1072.