老年人和非老年非静脉曲张性上消化道出血的病因和合并症特征比较

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Abstract Objective To enhance the ability to early identify non-variceal upper gastrointestinal bleeding(NVUGB) in the elderly.Methods A retrospective cohort study was performed by searching for medical reports on cases diagnosed with “NVUGB” between Jan 2015 and Jan 2017 via an electronic medical records management system.All the patients with NVUGB were divided into the elderly study group(≥60 years old) and control group(aged 18 to 59).The diagnostic clues , etiology, comorbidity and drugs used were compared between two groups.Results The incidence of haematemesis was markedly lower in the elderly group(15.2％) than that in the control group(23.4％, P<0.01), but the signs of hypovolemic state occurred more often in the elderly group than in the control group(10.6% vs 6.0%, P<0.05). 78.8% of the patients in the elderly group were diagnosed by gastrocopy, and 90.2% in the control group (P<0.01). The etiologies among these elderly patients included duodenal and gastric ulcers,and upper gastrointestinal malignancies, while in the control group upper gastrointestinal malignancies were dominating, followed by duodenal and gastric ulcers. Comorbidity (134/151) was more common in the elderly group than in the control group(78/112,P<0.01), including cardiovascular diseases and hypertension (P<0.01).Conclusion The main risk factors of NVUGB in the elderly are the high incidence of comorbidity and antiplatelet therapies.The etiologies are complex, including duodenal and gastric ulcers ,and upper gastrointestinal malignancies. Early gastrocopy is the key to positive diagnosis of NVUGB.

Key words： elderly upper gastrointestinal bleeding,non-variceal etiology comorbidity

Received: 11 October 2016

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	Articles by authors
	WU Wenjuan
	SHI Yingying
	CHEN Xiaoguang
	and WANG Weian

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WU Wenjuan,SHI Yingying,CHEN Xiaoguang等. Etiology and comorbidity of non-variceal upper gastrointestinal bleeding in the elderly: a retrospective cohort study[J]. Med. J. Chin. Peop. Armed Poli. Forc., 2017, 28(4): 344-346.

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http://journal08.magtechjournal.com/Jwk_wjyx/EN/ OR http://journal08.magtechjournal.com/Jwk_wjyx/EN/Y2017/V28/I4/344

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