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Comparison of short-term efficacy of minimally invasive esophagectomy and esophagectomy in the treatment of esophageal cancer |
SU Liwei, ZHANG Dongmei, LI Wei, XIAO Bo, YUE Hongxu, HE Shu, and NIU Zhongxi |
Department of Thoracic Surgery, the General Hospital of Chinese People’s Armed Police Force, Beijing 100039 , China |
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Abstract Objective To compare the short-term efficacy of minimally invasive esophagectomy (MIE) and esophageal carcinoma in the treatment of esophageal cancer.Methods A total of 60 patients with esophageal carcinoma admitted to our hospital between April 2015 and October 2016 were randomly divided into MIE group (30 cases) and esophagectomy group (30 cases). The time of operation, amount of blood loss, number of lymph nodes dissected, time the patient got out of bed for the first time, time of anus exhaust, drainage time of thoracic cavity, drainage volume of thoracic cavity, length of hospital stay, blood routine examinations on day 5, C reaction protein and pain assessment were compared between the two groups after treatment.Results There were no significant differences in baseline characteristics or in the number of lymph nodes dissected [(18.8±8.6) vs (16.2±8.4),P=0.24] between the two groups (P>0.05). MIE patients had a smaller bleeding volume (200±50) ml than those in the esophagectomy group (350 ± 150) ml (P<0.001), as was the case with pleural cavity drainage [(550±200) ml vs (800±350) ml,P<0.001]. Extubation was performed earlier than in the open group [(4.7±1.5) d vs (5.9±1.8) d, P<0.001].There was no significant difference between the two groups in terms of postoperative venting time [(2.1±1.3) d vs (2.3±1.5) d,P=0.27] and ambulation time [(1.2±0.8) d vs (1.3±0.6) d, P=0.52]. In the MIE group, the hospital stay was shorter than that in the open group [(5.2±1.6) d vs (9.4±1.8) d,P<0.001]. The VAS scores of the MIE group were (2.9±1.1), (2.1±1.0) and (1.5±0.8) respectively at 24 h, 48 h and 72 h after operation, which were significantly lower than those of the conventional open group (P<0.001).Conclusions MIE can significantly reduce the amount of bleeding in patients, alleviate pain, and shorten hospital stay after surgery. It can be used as a new surgical therapy for esophageal cancer.
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Received: 18 January 2017
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