|
|
Effect of Bailing capsules combined with eucalyptus lemon pinene enteric soft capsules on pulmonary function in patients with chronic obstructive pulmonary disease (COPD) |
ZOU Fenfang, GAO Hongmei, ZHANG Jianpeng, JIAO Hongbin |
Respiratory Department, The General Hospital of Chinese People's Armed Police Force, Beijing 100044,China |
|
|
Abstract Objective To investigate the therapeutic effect of Bailing capsules combined with eucalyptus lemon pinene enteric soft capsules on pulmonary function in patients with chronic obstructive pulmonary disease (COPD). Methods A total of 80 COPD patients admitted to our hospital between January 2013 and May 2014 were selected as subjects in this study. They were randomly divided into two groups.One group of patients was given Budesonide and Formoterol Fumarate powder plus regular COPD treatment (conventional treatment group, n=40), while the other group was given eucalyptus lemon pinene enteric soft capsules and Bailing capsules combined with conventional therapy (combined treatment group, n=40). The pulmonary function, including forced expiratory volume in one second (FEV1) and forced vital capacity rate of one second (FEV1/FVC), was tested in both groups of patients. The exercise capacity index and acute outbreak of COPD was recorded after six-month treatment. Results Compared with the conventional treatment group, the combined treatment group had significantly improved lung function and exercise capacity index(355.5±8.6), as was shown by elevated FEV1/FVC (62.6±7.6)%, and decreased times of acute outbreak(1.26±0.25)(P<0.05). Conclusions The effect of Bailing capsules combined with eucalyptus lemon pinene enteric soft capsules on pulmonary function in patients with COPD is significant.
|
Received: 21 May 2017
|
|
|
|
|
[1] |
Mac Nee W. Pathogenesis of chronic obstructive pulmonary disease [J]. Am J Respir Crit Care Med, 2005, 2:258-266.
|
[2] |
Rabe K, Hurd S, Anzueto A, et al . Global strategy for the diagnosis, management, and prevention of chronic obstmctive pulmonary disease: GOLD executive summary [J]. Am J Respir Crit Care Med, 2007, 176:532-555.
|
[3] |
郭美华,王 健,钟南山,等.氧化应激在慢性阻塞性肺疾病发病中的作用及机制研究[J].中华结核和呼吸杂志, 2015, 38(3): 222-224.
|
[4] |
杜 强,崔 进,蔡健康,等.百令胶囊对中重度慢性阻塞性肺病患者肺功能、气道炎症以及氧化应激的影响[J].南京医科大学学报(自然科学版),2015,35(1):58-61.
|
[5] |
中华医学会呼吸病学分会慢性阻塞性肺疾病学组. 慢性阻塞性肺疾病诊治指南(2013年修订版)[J]. 中华结核和呼吸杂志,2013,36 (4):255-264.
|
[6] |
ATS Committee on Proficiency Standards for Clinical Pulmonary Function Laboratories.ATS statement:Guidelines for the six-minute walk test [J].Am J Respir Crit Care Med,2002,166:111-117.
|
[7] |
Anthonisen N,Manfreda J,Warren C, et al .Antibiotic therapy in exacerbations of chronic obstructive pulmonary disease[J].Ann Intern Med, 1987, 106(2):196-204.
|
[8] |
许惠娟,李时悦.百令胶囊的药理作用及其在肺部疾病的研究进展[J].中国中药杂志,2010,35(20):2776-2781.
|
[9] |
韩书芝,平 芬,赵艳娟,等.百令胶囊对慢性阻塞性肺疾病患者氧化/抗氧化失衡的干预作用[J].中国现代医学杂志,2010,20(12):1841-1844.
|
[10] |
吕 静,王晓晟,杨 琳,等.百令胶囊对慢性阻塞性肺病患者的影响[J].临床肺科杂志,2014,19(5):890-891.
|
[11] |
柳 仙.桉柠蒎肠溶软胶囊的临床应用分析[J].医学理论与实践,2013,26(14):1944.
|
|
|
|