脑外伤合并不同程度获得性肺炎患者外周血T细胞亚群表达水平观察

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Abstract Objective To observe the expressions of T cell subsets in the peripheral blood of patients with traumatic brain injury (TBI) combined with hospital acquired pneumonia (HAP).Methods From January 2013 to June 2015, a total of 31 TBI inpatients combined with HAP were successively selected from the Department of Neurosurgery of Liaoning Provincial Corps Hospital. Meanwhile, another 19 inpatients diagnosed with TBI but without HAP were selected as the TBI group, and another 23 healthy physical examinees were assigned to the control group.The three groups of subjects were examined in terms of indexes for the T cell subsets (CD3⁺, CD4⁺, CD8⁺, CD4⁺/CD8⁺) in the peripheral blood.Results The expression levels of CD3⁺ and CD4⁺ in peripheral blood and the CD4⁺/CD8⁺ value in the TBI patients combined with HAP (52.71±5.24% and 29.30±3.15%,0.89±0.17)were obviously lower than those in the TBI group and the control group (Pall<0.05).On the other hand, the expression levels of CD3⁺ and CD4⁺ in peripheral blood and the CD4⁺/CD8⁺ value in the TBI patients combined with severe HAP(49.64±4.81%,28.76±3.04%,0.85±0.13)were obviously lower than those of TBI patients combined with mild HAP (P all<0.05).Conclusions TBI patients combined with HAP have definitely abnormal expressions of T cell subsets in peripheral blood that become more significant with the aggravation of disease.

Key words： traumatic brain injury hospital acquired pneumonia T cell subsets/peripheral blood

Received: 15 March 2018

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	YANG Hualin
	YANG Yueli

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YANG Hualin,YANG Yueli. Expressions of T cell subsets in peripheral blood of patients with traumatic brain injury combined with hospital acquired pneumonia[J]. Med. J. Chin. Peop. Armed Poli. Forc., 2018, 29(11): 1072-1074.

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http://journal08.magtechjournal.com/Jwk_wjyx/EN/ OR http://journal08.magtechjournal.com/Jwk_wjyx/EN/Y2018/V29/I11/1072

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