降钙素原、C反应蛋白、氨基末端脑钠肽前体预测老年肺炎患者发生房颤的价值

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Abstract Objective To compare the ability of procalcitonin, C-reactive protein(CRP) and N-terminal pro-B-type natriuretic peptide(NT-pro BNP) to predict the occurrence of atrial fibrillation in geriatric community acquired pneumonia(CAP) patients.Methods Geriatric patients with CAP or without infections were enrolled in this study and divided into two groups: CAP group and control group(non-infection group) , while patients with mitral stenosis and other diseases were excluded. These patients were examined with electrocardiograms and cardiac ultrasound and had their blood detected quickly. The incidence and types of atrial fibrillation were observed. The ability of the initial values and peak values three months after hospitalization of PCT、CRP and NT-proBNP to predict atrial fibrillation was calculated.Results A total of 156 male patients were enrolled, including 120 patients with CAP and 36 patients as control. Morbidity was higher in the CAP group. PCT had the highest positive predictive value for the occurrence of atrial fibrillation, while the initial diagnostic value of PCT and peak value of CRP after three months displayed the highest negative predictive value.Conclusions PCT may be a promising option to predict the chance of atrial fibrillation among geriatric patients of CAP in the early stage. Persistent negative values of CRP indicate less chance of atrial fibrillation.

Key words： community acquired pneumonia geriatrics atrial fibrillation biomarkers prediction

Received: 12 March 2019

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	GAN Zhuokun
	TIAN Haitao

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GAN Zhuokun,TIAN Haitao. Prediction of atrial fibrillation occurrence in pneumonia geriatrics with procalcitonin,C-reactive protein and NT-pro BNP[J]. Med. J. Chin. Peop. Armed Poli. Forc., 2019, 30(6): 488-492.

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http://journal08.magtechjournal.com/Jwk_wjyx/EN/ OR http://journal08.magtechjournal.com/Jwk_wjyx/EN/Y2019/V30/I6/488

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