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Correlations between body composition of early pregnant women and macrosomia risk |
ZHANG Can1,2, LIU Jie1, ZHANG Haiyan2, FAN Zhonggui2, LUO Li2, XU Hongxia1 |
1.Department of Clinical Nutrition, Daping Hospital, Army Medical University, Chongqing 400042, China; 2.Maternal Nutrition Clinic, Chongqing Yongchuan District Maternity and Child Health Hospital, Chongqing 402160, China |
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Abstract Objective To explore the association between body composition of early pregnant women and macrosomia risk.Methods We retrospectively included 1697 pregnant women who had given birth in Yongchuan Maternity and Child Health Hospital of Chongqing between January and September in 2016. Macrosomia related risk factors as well as body composition of early pregnant women were investigated and follow-up was performed until the cessation of pregnancy. Logistic regression analysis was used to explore the association between macrosomia and potential risk factors, including body composition of early pregnant women.Results BMI of early pregnancy, body fat weight and body fat percentage were independent risk factors for macrosomia. Fat-free mass was an independent protective factor. Early pregnant women with BMI≥28 were 3.75 times as likely to have macrosomic newborns as those with normal BMI (18.5-23.9). Similarly, pregnant women with fat weight greater than 0.28 times body weight were 4.21 times as vulnerable as those with fat weight less than 0.2 times body weight. Pregnant women with a body fat percentage≥30% were 1.86 times as vulnerable as those with a body fat percentage<30%. Pregnant women with fat-free mass greater than 0.8 times body weight had a 76% decreased risk for macrosomic newborns.Conclusions BMI and body composition of early pregnancy are associated with macrosomia risk. Nutrition and exercise interventions are recommended in those early pregnant women with obesity and excessive body fat to reduce the risk of macrosomia.
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Received: 02 May 2019
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