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Difference in cognitive impairment patterns by the Montreal Cognitive Assessment-Basic in patients of different age with mild cognitive impairment |
TANG Yu1, HAO Dandan1, QIN Weiting1, WEN Xiao1, LI Fang2 |
1.Department of Neurology, 2. Department of Gerontology, Fuxing Hospital, the Eighth Clinical Medical College, Capital Medical University, Beijing 100038, China |
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Abstract Objective To investigate the difference in the Montreal Cognitive Assessment-Basic(MoCA-B) sub-item scores between patients of different age with mild cognitive impairment(MCI).Methods One hundred and ninety MCI patients were recruited from the outpatients and inpatients of the Department of Neurology and surrounding communities between January 2017 and December 2017. Patients were divided into three groups according to their age: 50-59(n=47), 60-69(n=73) and 70-79(n=70). All the patients were subjected to a survey by means of Mini-Mental State Examination(MMSE)and MoCA-B.Results There was no significant difference between the three groups in gender, levels of education, MMSE or MoCA-B. When each item of MoCA-B was compared between the three groups, verbal fluency test(VFT) and delayed recall were significantly different(P<0.05). Patients under 60 got a little higher scores in VFT than those above 60(0.8±0.5 vs 0.5±0.6), but the difference was not statistically significant. For verbal delayed recall, the scores of the three groups were(1.1±1.0),(0.4±0.8) and(0.5±1.0),respectively. Patients under 60 got higher scores than older ones. The difference was significant between the three groups(P<0.05).Conclusions When interpreting the scores of each item of MoCA-B, we should pay attention to the possible influence of age, especially the verbal delayed recall score.
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Received: 01 May 2019
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[1] |
Ton T G N, DeLeire T, May S G, et al. The financial burden and health care utilization patterns associated with amnestic mild cognitive impairment [J]. Alzheimers Dement, 2017, 13(3):217-224.
|
[2] |
Sheikh F, Ismail Z, Mortby M E, et al. Prevalence of mild behavioral impairment in mildcognitive impairment and subjective cognitive decline, and its association with caregiver burden [J]. Int Psychogeriatr, 2018, 30(2):233-244.
|
[3] |
Petersen R C, Lopez O, Armstrong M J, et al. Practice guideline update summary: mild cognitive impairment: report of the guideline development, dissemination, and implementation subcommittee of the American Academy of neurology[J]. Neurology, 2018, 90 (8):126-135.
|
[4] |
Taragano F E, Allegri R F, Heisecke S L, et al. Risk of conversion to dementia in a mild behavioral impairment group compared to a psychiatric group and to a mild cognitive impairment group[J]. J Alzheimers Dis, 2018, 62(1):227-238.
|
[5] |
Nasreddine ZS, Phillips NA, Bédirian V, et al. The Montreal Cognitive Assessment, MoCA: a brief screening tool for mild cognitive impairment[J]. J Am Geriatr Soc, 2005, 53(4):695-699.
|
[6] |
冯荣芳, 刘惠卿, 贾艳丽, 等. MMSE和MoCA在不同类型轻度认知障碍筛查中的应用[J]. 脑与神经疾病杂志, 2015,23(5): 321-325.
|
[7] |
孔伶俐, 孙忠国, 周田田, 等. 蒙特利尔认知评估量表在轻度认知功能障碍诊断中的应用[J]. 中国健康心理学杂志, 2015,23(8):1212-1215.
|
[8] |
黄菲芸, 王艳红, 李娟娟, 等. 蒙特利尔认知评估量表在中国中老年人群筛查轻度认知功能障碍中的截断值的系统评价[J]. 中国循证医学杂志, 2017,17(4):450-457.
|
[9] |
潘晓东, 徐 俊, 周 辰, 等. 在老年人中简化蒙特利尔认知评估量表的初步尝试[J]. 中华老年心脑血管病杂志, 2018, 20(4):419-422.
|
[10] |
鸦明琴, 赵翔宇, 程俊芳. 北京版蒙特利尔认知评估量表应用于体检人群的相关因素分析[J]. 护理研究, 2018, 32: 814-816.
|
[11] |
Julayanont P, Tangwongchai S, Hemrungrojn S, et al. The Montreal Cognitive Assessment-Basic: A Screening Tool for Mild Cognitive Impairment in Illiterate and Low-Educated Elderly Adults[J]. J Am Geriatr Soc, 2015,63(12):2550-2554.
|
[12] |
Chen K L, Xu Y, Chu A Q, et al. Validation of the Chinese version of Montreal cognitive assessment basic for screening mild cognitive impairment[J]. J Am Geriatr Soc, 2016, 64(12): e285-e290.
|
[13] |
Espinosa A, Alegret M, Valero S, et al. A longitudinal follow-up of 550 mild cognitive impairment patients: evidence for large conversion to dementia rates and detection of major risk factors involved[J]. J Alzheimers Dis, 2015, 43(2): 335.
|
[14] |
Di C A, Baldereschi M, Lamassa M, et al. Daily Function as predictor of dementia in cognitive impairment, no dementia (CIND) and mild cognitive impairment (MCI): an 8-year follow-up in the ILSA study[J]. J Alzheimers Dis, 2016, 53(2): 505-515.
|
[15] |
Alves L, Cardoso S, Maroco J, et al. Neuropsychological predictors of long-term (10 years) mild cognitive impairment stability[J]. J Alzheimers Dis, 2018, 62(4): 1703-1711.
|
[16] |
Blazer D G,Yaffe K.,Liverman C T. Cognitive aging: progress in understanding and opportunities for action[J]. Mil Med, 2015, 180(11):1111-1113.
|
[17] |
Blazer D G, Wallace R B. Cognitive aging: what every geriatric psychiatrist should know[J]. Am J Geriatr Psychiatry, 2016, 24(9): 776-781.
|
[18] |
霍丽娟, 郑志伟, 李 瑾, 等. 老年人的脑可塑性:来自认知训练的证据[J]. 心理科学进展, 2018, 26(5): 846-858.
|
[19] |
Stolwyk R, Bannirchelvam B, Kraan C, et al. The cognitive abilities associated with verbal fluency task performance differ across fluency variants and age groups in healthy young and old adults [J]. J Clin Exp Neuropsychol, 2015, 37(1): 70-83.
|
[20] |
杨 群, 张清芳. 口语产生中的认知年老化及其神经机制[J]. 心理科学进展, 2015, 23(12):2072-2084.
|
[21] |
何文广. 语言认知老化机制及其神经基础[J]. 心理科学进展, 2017, 25(9): 1479-1491.
|
[22] |
Cipolotti L, Healy C, Chan E, et al. The effect of age on cognitive performance of frontal patients [J]. Neuropsychologia, 2015, 75:233-241.
|
[23] |
陈 衍, 刘香倩, 符 虔. 认知老化模型及其脑成像研究进展[J]. 中国老年学杂志, 2016, 36(2): 492-495.
|
[24] |
Tang E Y, Brayne C, Albanese E, et al. Mild cognitive impairment definitions: more evolution than revolution [J]. Neurodegener Dis Manag, 2015, 5(1): 11-17.
|
[25] |
王予灵, 汪凤炎. 老者智否?成人智慧与年龄的关系[J]. 心理科学进展, 2018, 26(1): 107-117.
|
|
|
|