平均血小板体积与ST段抬高型心肌梗死患者血尿酸水平的相关性

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Abstract Objective To investigate the relationships between the mean platelet volume (MPV) and serum uric acid (UA) levels in patients with ST-segment elevation myocardial infarction (STEMI).Methods A total of 322 patients with STEMI were enrolled in this study between February 2016 and March 2018 in Xuanwu Hospital, with an average age of (62.74±11.60)years old. These STEMI patients were divided into the hyperuricemia (HUA) group (n=66) and normal UA group (n=256) according to serum uric acid levels. Pearson analysis was used to analyze the relationships between the MPV and UA levels. Also, multivariate linear regression and Logistic regression were performed to analyze the correlations between the MPV and UA levels in STEMI patients.Results Age, body mass index (BMI), white blood cells (WBC), MPV, serum creatinine (SCr),and blood urea nitrogen (BUN) in HUA group were significantly above those in the normal UA group with a P-value less than 0.05. Pearson analysis showed that the MPV was positively correlated with UA levels (r=0.448, P=0.000). Multivariate regression analysis showed that BMI, red blood cells (RBC), MPV, SCr, BUN and triglyceride (TG) were positively correlated with UA levels (P＜0.05). Logistic regression analysis showed that the MPV (OR=2.415, 95%CI 1.681-3.470, P=0.000) was an independent risk factor for serum UA levels.Conclusions The MPV in STEMI patients is positively correlated with UA, and may be one of the risk factors for HUA in STEMI patients.

Key words： ST-segment elevation myocardial infarction uric acid mean platelet volume hyperuricemia

Received: 20 June 2019

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	ZHANG Ruixue
	YAN Feng
	SUN Xipeng

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ZHANG Ruixue,YAN Feng,SUN Xipeng. Relationships between mean platelet volume and serum uric acid in patients with ST-segment elevation myocardial infarction[J]. Med. J. Chin. Peop. Armed Poli. Forc., 2019, 30(12): 1047-1050.

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http://journal08.magtechjournal.com/Jwk_wjyx/EN/ OR http://journal08.magtechjournal.com/Jwk_wjyx/EN/Y2019/V30/I12/1047

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