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Effect of cerebral vascular bypass surgery on early postoperative cognitive function in patients with moyamoya disease under different anesthesia methods |
ZHANG Qing, WANG Lixin, YUE Hongli, YU Yun |
Department of Anesthesiology, Beijing Tiantan Hospital, Capital Medical University, Beijing 100070, China |
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Abstract Objective To explore the effect of cerebral vascular bypass surgery on early postoperative cognitive functions in patients with moyamoya disease under intravenous anesthesia and inhalation anesthesia. Methods A total of 74 patients with moyamoya disease were divided into the total intravenous anesthesia group (T Group) and inhalation anesthesia group (I group). All the patients received cerebral vascular bypass surgery. The cognitive functions of patients were assessed before surgery and 7 days after surgery by mini mental state examination (MMSE) and Montreal Cognitive Assessment (MoCA). General anesthesia was performed during the operations. Results After operation, there was no significant difference in MMSE scores of patients’ cognitive functions. As for MoCA scores, only memory function improved obviously in both groups, and the difference was statistically significant (P<0.05). There was no significant difference between the two groups in other aspects. Conclusions Vascular bypass surgery can improve the early memory function in patients with moyamoya disease, but has no significant influence on other cognitive functions. Neither total intravenous anesthesia nor inhalation anesthesia makes much difference to the early cognitive function of patients after cerebral vascular bypass surgery.
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Received: 08 September 2019
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