S-T段抬高型心肌梗死及合并心源性休克患者急诊PCI术中血运重建策略的荟萃分析

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Abstract Objective To provide evidence-based medical evidence for primary PCI in STEMI patients. Methods Papers published in the Medline, Pubmed, Web of Science, Clinicaltrials.gov, CNKI, Wanfang, and SinoMed before June 2019 were retrieved and screened out via computers while the Jadad score was used to assess the quality of the papers. Meta-analysis was performed with the random effects model, and publication bias was assessed with Egger regression analysis. Results A total of 3,617 patients from 13 studies were enrolled, 1,817 of whom underwent complete revascularization. For STEMI patients, the incidence of MACE (RR=0.562, 95% CI:0.47-0.68, P<0.001), all-cause death (RR=0.654, 95% CI:0.53-0.82, P<0.001) and revascularization rate (RR=0.495, 95% CI: 0.36-0.68, P<0.001) in the complete revascularization group were significantly reduced, but there was no significant difference in the incidence of recurrent myocardial infarction. For AMI patients with cardiogenic shock, complete revascularization reduced the incidence of MACE (RR=0.764, 95% CI: 0.60-0.98, P=0.034). The publication bias was not significant. Conclusions Complete revascularization can reduce the incidence of major cardiovascular adverse events, all-cause death and revascularization in patients with S-T segment elevation myocardial infarction. For acute myocardial infarction patients with cardiogenic shock, complete revascularization can reduce the incidence of major cardiovascular adverse events.

Key words： acute myocardial infarction S-T segment elevated myocardial infarction percutaneous coronary intervention complete revascularization

Received: 30 December 2019

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	LI Chuang
	CHU Yushun
	WU Guodong
	ZHANG Mei

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LI Chuang,CHU Yushun,WU Guodong等. Meta-analysis of revascularization strategies for STEMI patients during primary PCI[J]. Med. J. Chin. Peop. Armed Poli. Forc., 2020, 31(5): 389-393.

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http://journal08.magtechjournal.com/Jwk_wjyx/EN/ OR http://journal08.magtechjournal.com/Jwk_wjyx/EN/Y2020/V31/I5/389

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