胸部超声降钙素肺部感染评分法对呼吸机相关性肺炎的诊断价值

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Abstract Objective To evaluate the diagnostic performance of the chest echography and procalcitonin pulmonary infection score(CEPPIS) of patients with ventilator-associated pneumonia(VAP).Methods Patients who were on mechanical ventilation in the intensive care unit (ICU) of Army Medical Center and met the inclusion criteria were included in this study. These patients were divided into the VAP group and control group according to the culture results of bronchial microorganisms (with nosocomial infection and total bacterial colonies>10⁵/ml). Demographic information, clinical features and prognosis were compared via statistical analysis. The CEPPIS and clinical pulmonary infection score(CPIS) were graded using indicators including pulmonary echography, bedside chest radiography, procalcitonin and sputum culture when patients experienced dyspnea or decreased oxygenation. A receiver operating characteristic (ROC) analysis was conducted of CEPPIS, CPIS and procalcitonin to evaluate their diagnostic performance.Results A total of 144 patients were included with 71 patients in the VAP group and 73 in the control group. 93(64.6%) of them were males, and the average age was 54.35 years with a standard deviation of 21.49. The area under curve(AUC) of CEPPIS>5 was 0.846(95%CI:0.775-0.916,P<0.01), greater than 0.713 of CPIS>6 (95%CI:0.625-0.800, P<0.01) and 0.557 of PCT>1 ng/ml(95% CI:0.463-0.652,P=0.048).Conclusions The diagnostic performance of CEPPIS is possibly better than that of CPIS and PCT, but more research is needed to investigate its diagnostic efficiency.

Key words： ventilator-associated pneumonia echography procalcitonin scores diagnostic performance

Received: 27 April 2020

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	Articles by authors
	ZHU Qian
	DU Juan
	HUANG Xiaoying
	WEN Dalin
	LUO Li
	PENG Xiaoyu
	GAN Ping
	TANG Hao

Cite this article:

ZHU Qian,DU Juan,HUANG Xiaoying等. Applicability of chest echography and procalcitonin pulmonary infection score(CEPPIS) in patients with ventilator-associated pneumonia(VAP)[J]. Med. J. Chin. Peop. Armed Poli. Forc., 2020, 31(8): 649-653.

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http://journal08.magtechjournal.com/Jwk_wjyx/EN/ OR http://journal08.magtechjournal.com/Jwk_wjyx/EN/Y2020/V31/I8/649

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