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Predictive value of SYNTAX scoreⅡ for clinical outcomes in patients with acute ST-segment elevation myocardial infarction |
XI Ke1, WANG Li2, LIU Hui1 |
1. The Weigong Bridge Outpatient Department, Jingxi Medical Section, PLA General Hospital, Beijing 100089, China; 2. Department of Medical Affairs, Beijing Public Security Hospital, Beijing 100121, China |
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Abstract Objective To investigate the predictive value of the SYNTAX score Ⅱ for clinical outcomes in patients with acute ST-segment elevation myocardial infarction.Methods A total of 445 acute STEMI patients receiving the PCI therapy within 12 hours between January 1, 2014 and June 30, 2016 were enrolled in this study. SYNTAX score Ⅱ was calculated,while major adverse cardiac events were recorded. These patients were divided into the low score group and the high score group. The effects of each clinical correlation factor were compared between the two groups of patients, so were the incidence and mortality of endpoint events. The influencing factors and independent influencing factors of all-cause mortality in patients with acute STEMI were analyzed.Results The difference between the two groups was statistically significant (P<0.05) in age, gender, smoking history, ejection fraction, Killip grade, and in incidence and mortality of endpoint events. Univariate analysis showed that age, smoking history, ejection fraction, serum creatinine, KillipⅡ-Ⅳ and SYNTAX scoreⅡ were factors that influenced the all-cause mortality of patients with acute STEMI. Cox regression analysis showed that age(OR=1.696,95% CI 1.037-2.359) , ejection fraction(OR=0.810,95% CI 0.713-0.907), SYNTAX scoreⅡ(OR=1.309,95% CI 1.132-1.317) were independent influencing factors of the all-cause mortality of patients with acute STEMI.Conclusions SYNTAX scoreⅡ is an independent risk factor for all-cause mortality in patients with acute STEMI. The higher SYNTAX scoreⅡ in patients with acute STEMI, the more chance of MACE, the earlier occurrence of MACE, the higher mortality.
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Received: 20 November 2019
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