宫颈癌术前动脉介入化疗栓塞与全身化疗的疗效比较

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Abstract Objective To compare and analyze the effects of preoperative transcatheter arterial chemoembolization and systemic chemotherapy on tumor resection rates and quality of life of patients with cervical cancer.Methods One hundred and thirteen patients with cervical cancer treated in our hospital between January 2013 and February 2019 were divided into two groups according to treatments. The intervention group (n=58) was treated with transcatheter arterial chemoembolization before surgery, while the chemotherapy group (n=55) received systemic chemotherapy preoperatively. The tumor resection rate and quality of life were compared between the two groups.Results The duration of surgery, radical operation rate, intraoperative blood loss and lymph node metastasis rate in the intervention group were significantly different from those of the chemotherapy group (P<0.05). The levels of serum VEGF-D, VEGF-C and VEGF-A in the two groups were lower after operation, and the difference was statistically significant. The levels of serum VEGF-D, VEGF-C and VEGF-A in the intervention group were lower than those of the chemotherapy group after operation, and the difference was also statistically significant. There was no significant difference in the total score of quality of life between the two groups one year after operation (P>0.05).Conclusions Preoperative transcatheter arterial chemoembolization and systemic chemotherapy can significantly improve the tumor resection rate of patients with cervical cancer, and it is an excellent means of chemotherapy.

Key words： preoperative transcatheter arterial chemoembolization systemic chemotherapy cervical cancer tumor resection rate quality of life

Received: 21 August 2020

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R711.74

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	Articles by authors
	ZHANG Xiaofeng
	ZHAO Weijing
	DU Jing
	YUAN Yun

Cite this article:

ZHANG Xiaofeng,ZHAO Weijing,DU Jing等. Comparison of effects of preoperative transcatheter arterial chemoembolization and systemic chemotherapy on tumor resection rate and quality of life in patients with cervical cancer[J]. Med. J. Chin. Peop. Armed Poli. Forc., 2020, 31(10): 849-852.

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http://journal08.magtechjournal.com/Jwk_wjyx/EN/ OR http://journal08.magtechjournal.com/Jwk_wjyx/EN/Y2020/V31/I10/849

[1]	邹丽莎.术前子宫动脉介入化疗栓塞术在中晚期宫颈癌中的应用效果[J].中国当代医药,2019,26(32):78-81.
[2]	刘静,刘佳囡,张军辉, 等.系统人文关怀对经动脉化疗栓塞介入治疗的宫颈癌患者心率和收缩压及生活质量的影响[J].检验医学与临床,2019,16(17):2543-2546.
[3]	加静,艾绍庆.多西他赛静脉化疗联合奈达铂动脉介入栓塞治疗中晚期宫颈癌的临床效果[J].临床医学研究与实践,2019,4(25):36-38.
[4]	陈丰华,吴萍,郑媛, 等.Ⅰb2～Ⅱa2期宫颈癌患者术前经动脉介入栓塞化疗的疗效观察[J].中国药师,2019,22(7):1300-1302.
[5]	段甜.经皮动脉化疗药物灌注和栓塞介入治疗宫颈癌的护理探讨[J].海峡药学,2018,30(5):252-253.
[6]	杨卉.术前子宫动脉介入化疗栓塞术对宫颈癌患者肿瘤切除率及生存质量的影响[J].河北医药,2017,39(23):3530-3533,3538.
[7]	李晓红,张利娜.术前超选子宫动脉化疗栓塞抑制局部晚期宫颈癌病灶内癌细胞浸润性生长的研究[J].海南医学院学报,2018,24(11):1113-1116.
[8]	石成良,曾自力,沈永奇,等.调强放疗结合后装放疗联合介入化疗栓塞治疗局部晚期宫颈癌的疗效观察[J].中国现代医学杂志,2014,24(18):85-88.
[9]	孙静莉.术前选择性子宫动脉化疗栓塞用于宫颈癌的临床疗效分析[J].实用癌症杂志,2018,33(3):493-496.
[10]	陈金龙.宫颈癌子宫动脉化疗栓塞后手术切除的疗效分析[J].河北医药,2015,(9):1334-1336.
[11]	吴利荣,韩阳,谭明,等.髂内动脉灌注化疗与子宫动脉化疗栓塞晚期宫颈癌的临床疗效对比[J].实用癌症杂志,2018,33(2):336-339.
[12]	吴普照,张跃伟,赵广生,等.介入栓塞宫颈癌出血伴异位卵巢动脉供血并左髂内动脉缺如一例[J].介入放射学杂志,2014,23(3):230-231.
[13]	邹丽莎. 术前子宫动脉介入化疗栓塞术在中晚期宫颈癌中的应用效果[J].中国当代医药, 2019(32).
[14]	白星.子宫动脉介入化疗栓塞在40例中晚期宫颈癌临床应用[J].河南医学高等专科学校学报, 2018, 30(1): 9-11.
[15]	夏利花,余晓,汪锡耀. 动脉栓塞介入化疗治疗宫颈癌的临床分析[J].中国现代医生, 2011(13):25-26.