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Analysis of clinical and pathogenic characteristics of pyogenic liver abscess in a single center |
MA Zhigang, LI Zhide, LI Yupeng, CHEN Lunjian, BAHETI Kalifu, MENG Yuan, CHEN Xiong |
Department of hepatobiliary surgery, Xinjiang Uygur Autonomous Region People’s Hospital, Urumqi 830001,China |
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Abstract Objective To explore the clinical characteristics and pathogenic classification of 221 cases of patients with pyogenic liver abscess in Xinjiang Uygur Autonomous Region People’s Hospital.Methods The clinical data and microbiological data of 221 cases of patients with pyogenic liver abscess from January 2015 to January 2020 were collected retrospectively. After analysis of general information of 221 cases of patients with pyogenic liver abscess, the Chi-square test or Fisher test was used for comparison of clinical data between Klebsiella pneumoniae strains group and non-Klebsiella pneumoniae strains group; the logistic regression analysis was used for analyze risk factors for liver abscess caused by Klebsiella pneumoniae.Results Percutaneous drainage and drugs were performed in 189 cases of patients, laparoscopic resection of liver abscess following the percutaneous drainage and drugs due to the failure in 9 cases of patients, drugs alone in 23 cases of patients. Compared with non-Klebsiella pneumoniae strains group, the percentage of diabetes and alcoholism, treatment with drugs and percutaneous drainage, septic shock and the liver abscess in 5-10 cm in the diameter were higher in Klebsiella pneumoniae strains. Diabetes and alcoholism were the risk factors of liver abscess caused by Klebsiella pneumoniae strains.Conclusions Klebsiella pneumoniae strains is main pathogenic bacteria of pyogenic liver abscess, and diabetes and alcoholism are the risk factors of Klebsiella pneumoniae liver abscess, which shows more severe invasiveness and difficult treatment.
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Received: 10 August 2020
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