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Influence of different hemostatic methods on ovarian function during laparoscopic ovarian endometriosis cystectomy |
XU Wan1, LU Cuimin1, WANG Limei1, WEI Teman2, WANG Shuhe1 |
1. Department of Gynaecology and Obstetrics, the Seventh Medical Center of PLA General Hospital, Beijing 100700,China; 2. Department of Gynaecology and Obstetrics, Beijing Luhe Hospital,Capital Medical University, Beijing 101149,China |
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Abstract Objective To investigate the effect of different hemostatic methods on ovarian reserve function during laparoscopic ovarian endometriosis cystectomy.Methods Sixty patients who underwent laparoscopic cystectomy for ovarian endometriosis in the Seventh Medical Center of Chinese PLA General Hospital were selected. They were randomly divided into two groups: the suture group (30 cases) in which the suture method was used and the electrocoagulation group (30 cases) in which the bipolar electrocoagulation method was adopted. The changes of levels of estradiol (E2), luteinizing hormone (LH), follicle-stimulating hormone (FSH), and anti-mullerian hormone (AMH) in the two groups at different time points were compared.Results (1) The AMH values of the electrocoagulation group at each time point after operation were lower than those of the suture group, and the difference was statistically significant[three days after operation, one month after operation, three months after operation, and six months after operation, (1.6±1.2) ng/ml vs (2.5±1.6) ng/ml, (1.7±1.3) ng/ml vs (2.5±1.5) ng/ml, (2.9±1.6) ng/ml vs (3.7±1.1) ng/ml, (3.1±1.4) ng/ml vs (4.0±1.3)ng/ml respectively, P values were 0.017, 0.031, 0.028, 0.012 respectively]. In both groups, the AMH values were lower at three days and one month after operation, and the difference was also statistically significant. The AMH values in the suture group increased at six months after operation, and the difference was statistically significant (P<0.05). (2) Compared with preoperative FSH values in both groups at three days and one month after operation, the FSH level increased, and the difference was statistically significant (P<0.01). (3) The postoperative 3d LH values in both groups increased, and the difference was statistically significant (P<0.01).Conclusions Suture hemostasis is more conducive to the protection of ovarian reserve function than electrocoagulation hemostasis. AMH is a better indicator of ovarian reserve function than FSH.
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Received: 05 April 2020
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