|
|
|
|
|
Received: 14 February 2020
|
|
|
|
|
|
| [1] |
Sotiropoulos I,Silva J,Kimura T,et al.Female hippocampus vulnerability to environmental stress,a precipitating factor in Tau aggregation pathology[J].J Alzheimers Dis,2015,43(3):763-774.
|
| [2] |
Caceres G,McGraw K,Yip BH,et al.TP53 suppression promotes erythropoiesis in del(5q) MDS,suggesting a targeted therapeutic strategy in lenalidomide-resistant patients[J].Proc Natl Acad Sci U S A,2013,110(40):16127-16132.
|
| [3] |
Lazaro I,Oguiza A,Recio C,et al.Targeting HSP90 ameliorates nephropathy and atherosclerosis through suppression of NF-κB and STAT signaling pathways in diabetic mice[J].Diabetes,2015,64(10):3600-3613.
|
| [4] |
Zheng ZG,Zhang X,Liu XX,et al.Inhibition of HSP90β improves lipid disorders by promoting mature SREBPs degradation via the ubiquitin-proteasome system[J].Theranostics,2019,9(20):5769-5783.
|
| [5] |
黄德斌,翟 鑫,李晓行.HSP90-eNOS在糖尿病大鼠胸主动脉的表达及普罗布考干预实验[J].医学信息,2017,30(7):26-28.
|
| [6] |
任 静,曾海峰,夏 炜,等.热休克蛋白90促进糖尿病创面愈合的作用研究[J].中国美容医学,2010,19(5):691-694.
|
| [7] |
You Z,Zhang Z,Blagg B,et al.KU-596 decreases mitochondrial superoxide and improves bioenergetics following downregulation of manganese superoxide dismutase in diabetic sensory neurons[J].Exp Neurol,2019,313:88-97.
|
| [8] |
Kim D S,Song L,Wang J,et al.GRP94 is an essential regulator of pancreatic β-Cell development mass and function in male mice[J].Endocrinology,2018,159(2):1062-1073.
|
| [9] |
Ghiasi S M,Dahlby T,Hede Andersen C,et al.Endoplasmic reticulum chaperone glucose-regulated protein 94 is essential for proinsulin handling[J].Diabetes,2019,68(4):747-760.
|
| [10] |
Zhang X,Zhong Z,Li W.Downregulation of TRAP1 aggravates injury of H9c2 cardiomyocytes in a hyperglycemic state[J].Exp Ther Med.2019,18(4):2681-2686.
|
| [11] |
Kitano S,Kondo T,Matsuyama R,et al.Impact of hepatic HSP72 on insulin signaling[J].Am J Physiol Endocrinol Metab,2019,316(2):E305-E318.
|
| [12] |
Alemi H,Khaloo P,Rabizadeh S,et al.Association of extracellular heat shock protein 70 and insulin resistance in type 2 diabetes;independent of obesity and C-reactive protein.[J].Cell Stress Chaperones,2019,24(1):69-75.
|
| [13] |
Krause M,Heck TG,Bittencourt A,et al.The chaperone balance hypothesis:the importance of the extracellular to intracellular HSP70 ratio to inflammation-driven type 2 diabetes,the effect of exercise,and the implications for clinical management[J].Mediators Inflamm,2015,2015:249205.
|
| [14] |
Heidari F,Rabizadeh S,Sadat Salehi S,et al.Serum HSP70 level in patients with endometrial cancer with and without diabetes[J].Gynecol Endocrinol,2019,36(4):351-355.
|
| [15] |
Islam A,Hait S H,Andrews-Shigaki B,et al.Plasma HSP70 levels correlate with health risk factors and insulin resistance in African American subjects[J].Exp Clin Endocrinol Diabetes,2014,122(8):496-501.
|
| [16] |
Krause M,Keane K,Rodrigues-Krause J,et al.Elevated levels of extracellular heat-shock protein 72 (eHSP72) are positively correlated with insulin resistance in vivo and cause pancreatic β-cell dysfunction and death in vitro[J].Clin Sci (Lond),2014,126(10):739-752.
|
| [17] |
胡丽芳,黄文珍,刘 彤.妊娠期糖尿病孕妇血清HSP70水平升高并促进胎盘间质纤维化[J].临床与病理杂志,2018,38(10):2159-2165.
|
| [18] |
Sabbah N A,Rezk N A,Saad M S.Relationship between heat shock protein expression and obesity with and without metabolic syndrome[J].Genet Test Mol Biomarkers,2019,23(10):737-743.
|
| [19] |
Ohno Y,Yamada S,Sugiura T,et al.A possible role of NF-kappaB and HSP72 in skeletal muscle hypertrophy induced by heat stress in rats[J].Gen Physiol Biophys,2010,29(3):234-242.
|
| [20] |
Moniruzzaman M,Ahmed I,Huq S,et al.Association of polymorphism in heat shock protein 70 genes with type 2 diabetes in Bangladeshi population[J].Mol Genet Genomic Med,2020,8(2):e1073.
|
| [21] |
Mir K A,Pugazhendhi S,Paul M J,et al.Heat-shock protein 70 gene polymorphism is associated with the severity of diabetic foot ulcer and the outcome of surgical treatment[J].Br J Surg,2009,96(10):1205-1209.
|
| [22] |
Shepherd D L,Hathaway Q A,Nichols C E,et al.Mitochondrial proteome disruption in the diabetic regulation at the mitochondrial heat shock protein 70 (mtHsp70) nuclear locus[J].J Mol Cell Cardiol,2018,119:104-115.
|
| [23] |
Sayed K M,Mahmoud A A.Heat shock protein-70 and hypoxia inducible factor-1α in type 2 diabetes mellitus patients complicated with retinopathy[J].Acta Ophthalmol,2016,94(5):e361-e366.
|
| [24] |
Singh K,Agrawal N K,Gupta S K,et al.Decreased expression of heat shock proteins may lead to compromised wound healing in type 2 diabetes mellitus patients[J].J Diabetes Complications,2015,29(4):578-588.
|
| [25] |
Ma J,Farmer K L,Pan P,et al.Heat shock protein 70 is necessary to improve mitochondrial bioenergetics and reverse diabetic sensory neuropathy following KU-32 therapy[J].J Pharmacol Exp Ther,2014,348(2):281-292.
|
| [26] |
Chen Y W,Hsieh P L,Chen Y C,et al.Physical exercise induces excess hsp72 expression and delays the development of hyperalgesia and allodynia in painful diabetic neuropathy rats[J].Anesth Analg,2013,116(2):482-490.
|
| [27] |
Sell H,Poitou C,Habich C,et al.Heat shock protein 60 in obesity:effect of bariatric surgery and its relation to inflammation and cardiovascular risk[J].Obesity (Silver Spring),2017,25(12):2108-2114.
|
| [28] |
Märker T,Sell H,Zillessen P,et al.Heat shock protein 60 as a mediator of adipose tissue inflammation and insulin resistance[J].Diabetes,2012,61(3):615-625.
|
| [29] |
Khadir A,Kavalakatt S,Cherian P,et al.Physical exercise enhanced heat shock protein 60 expression and attenuated inflammation in the adipose tissue of human diabetic obese[J].Front Endocrinol (Lausanne),2018,9:16.
|
| [30] |
Rong J X,Qiu Y,Hansen M K,et al.Adipose mitochondrial biogenesis is suppressed in db/db and high-fat diet-fed mice and improved by rosiglitazone[J].Diabetes,2007,56(7):1751-1760.
|
| [31] |
Hall L,Martinus R D.Hyperglycaemia and oxidative stress upregulate HSP60 &HSP70 expression in HeLa cells[J].Springerplus,2013,2:431.
|
| [32] |
Aluksanasuwan S,Sueksakit K,Fong-Ngern K,et al.Role of HSP60 (HSPD1) in diabetes-induced renal tubular dysfunction:regulation of intracellular protein aggregation,ATP production,and oxidative stress[J].FASEB J,2017,31(5):2157-2167.
|
| [33] |
Weitgasser R,Lechleitner M,Koch T,et al.Antibodies to heat-shock protein 65 and neopterin levels in patients with type 1 diabetes mellitus[J].Exp Clin Endocrinol Diabetes,2003,111(3):127-131.
|
| [34] |
Cherian P T,Al-Khairi I,Sriraman D,et al.Increased circulation and adipose tissue levels of DNAJC27/RBJ in obesity and type 2-diabetes[J].Front Endocrinol (Lausanne),2018,9:423.
|
| [35] |
Abu-Farha M,Cherian P,Al-Khairi I,et al.DNAJB3/HSP-40 cochaperone improves insulin signaling and enhances glucose uptake in vitro through JNK repression[J].Sci Rep,2015,5:14448.
|
| [36] |
Abubaker J,Tiss A,Abu-Farha M,et al.DNAJB3/HSP-40 cochaperone is downregulated in obese humans and is restored by physical exercise[J].PLoS One,2013,8(7):e69217.
|
| [37] |
Synofzik M,Haack T B,Kopajtich R,et al.Absence of BiP Co-chaperone DNAJC3 Causes Diabetes Mellitus and Multisystemic Neurodegeneration[J].Am J Hum Genet,2014,95(6):689-697.
|
| [38] |
Jaroszyński A,Jaroszyńska A,Zaborowski T,et al.Serum heat shock protein 27 levels predict cardiac mortality in hemodialysis patients[J].BMC Nephrol,2018,19(1):359.
|
| [39] |
Li S,Liang M,Pan Y,et al.Exercise modulates heat shock protein 27 activity in diabetic cardiomyopathy[J].Life Sci,2020,243:117251.
|
| [40] |
许建斌,谢茂松,胡建章,等.早期糖尿病大鼠视网膜Hsp27表达的研究[J].中国实用眼科杂志,2015,33(3):307-310.
|
| [41] |
苏 石,李小承,马 茂,等.热休克蛋白B8与糖代谢异常的相关性研究[J].西安交通大学学报(医学版),2019,40(02):269-272,293.
|
|
|
2020, Vol. 31 
