利多卡因乳膏介导体外冲击波治疗带状疱疹后神经痛的可行性及有效性

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Abstract Objective To evaluate the clinical feasibility and efficacy of lidocaine cream being used as a divergent extracorporeal shock wave therapy(ESWT) for postherpetic neuralgia. Methods Ninety patients with non-head and face postherpetic neuralgia were randomly divided into two groups using the block randomization method.The treatment group(n=45) received lidocaine cream-mediated ESWT while the control group(n=45) was treated with ultrasonic couplant-mediated ESWT.Both groups received medication,ESWT,pulsed radiofrequency and nerve block. The Visual Analogue Scale(VAS),hyperalgesia,Hamilton Depression Scale(HAMD),doses of opioids and pregabalin and adverse reactions were observed in both groups for 12 weeks. Results Pain score comparison: Immediately after treatment and 2 weeks after treatment, the Visual Analogue Scale (VAS) of the treatment group was 1.96±0.77 and 2.25±0.89 respectively, compared with 2.97±0.79 and 3.40±0.81 in the control group. The doses of oxycodone and pregabalin were lower in the treatment group than in the control group.There were no complications related to ESWT in either group. Conclusions Our data suggests that lidocaine cream-mediated ESWT is effective and safe for PHN patients, which can be used as a supplementary treatment of PHN in grassroots hospitals.

Key words： postherpetic neuralgia divergent extracorporeal shock wave therapy lidocaine cream

Received: 11 November 2020

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	SUN Fuguo
	YE Ling
	CHEN Lu
	LIU Hui

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SUN Fuguo,YE Ling,CHEN Lu等. Feasibility and efficacy of lidocaine cream-mediated extracorporeal shock wave therapy for postherpetic neuralgia[J]. Med. J. Chin. Peop. Armed Poli. Forc., 2021, 32(3): 205-208.

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http://journal08.magtechjournal.com/Jwk_wjyx/EN/ OR http://journal08.magtechjournal.com/Jwk_wjyx/EN/Y2021/V32/I3/205

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