0.01%阿托品滴眼液对儿童近视眼的疗效及安全性

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Abstract Objective To observe the clinical effect and safety of 0.01% atropine eye drops among children with myopia. Methods Patients with myopia treated with 0.01% atropine eye drops were included in the study (30 cases, 59 eyes). 4 cases (8 eyes) were out of contact during the last follow-up, so 26 cases (51 eyes) were included in the statistical analysis. Meanwhile, other myopic children (18 cases, 36 eyes) who wore glasses only were selected as the control group. The changes of intraocular pressure, tear film break-up time (BUT), tear meniscus height (TMH), and dry eye questionnaire scores after three and after 6 months of treatment with eye drops were compared between the two groups.Results (1)There was statistically significant significance in diopter between the test group (-2.81±1.25) D and the control group (-3.38±1.24)D after six months of treatment. (2) There was no statistically significant significance in intraocular pressure [(20.18±5.21)mmHg vs. (20.97±5.12) mmHg], in BUT [(7.65±3.51)s vs. (7.21±3.12)s], in TMH [(0.24±0.05) mm vs. (0.26±0.05)mm], or in dry eye questionnaire scores (4.62±0.66 vs. 4.65±0.64) between the two groups. (3)No photophobia, near sightedness, allergy and other adverse reactions were observed during the six months of medication.Conclusions Six-month topical use of 0.01% atropine eye solution for 6 months can deliver satisfactory efficacy and safety.

Key words： 0.01% atropine eye drops tear meniscus height adverse reaction intraocular pressure dry eye

Received: 20 December 2020

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	Articles by authors
	ZHAO Hongwei
	ZHAO Bingyi
	GUO Shichao
	WANG Yuan
	ZHU Caixia
	XIA Liping

Cite this article:

ZHAO Hongwei,ZHAO Bingyi,GUO Shichao等. The therapeutic effect and safety of 0.01% atropine eye drops among children with myopia[J]. Med. J. Chin. Peop. Armed Poli. Forc., 2021, 32(6): 472-475.

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http://journal08.magtechjournal.com/Jwk_wjyx/EN/ OR http://journal08.magtechjournal.com/Jwk_wjyx/EN/Y2021/V32/I6/472

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